GABARAPL1

Gene Symbol GABARAPL1
Entrez Gene 23710
Alt Symbol APG8-LIKE, APG8L, ATG8, ATG8B, ATG8L, GEC1
Species Human
Gene Type protein-coding
Description GABA(A) receptor-associated protein like 1
Other Description GABA(A) receptor-associated protein-like 1|GABARAPL1-a|GEC-1|early estrogen-regulated protein|gamma-aminobutyric acid receptor-associated protein-like 1|glandular epithelial cell protein 1
Swissprots Q6FIE6 B4E0Y7 Q9H0R8
Accessions EAW96164 EAW96165 EAW96166 EAW96167 EAW96168 EAW96169 EAW96170 Q9H0R8 AF087847 AAK20399 AF287012 AAK55962 AK056846 AK074195 AK092075 AK124150 AK303581 BAG64599 AK315418 BAG37807 AL136676 CAB66611 AM393185 CAL38063 AM393189 CAL38067 BC008891 BC009309 AAH09309 BC028315 AAH28315 BX648781 CR533480 CAG38511 DQ893103 ABM84029 DQ896375 ABM87374 JN663881 AEZ06294 XM_005253344 XP_005253401 NM_031412 NP_113600
Function Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000269|PubMed:16431922, ECO:0000269|PubMed:20404487}.
Subcellular Location Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Lipid-anchor. Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, autophagosome.
Tissue Specificity Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particularly intense in motoneurons in the embryo and in neurons involved in somatomotor and neuroendocrine functions in the adult, particularly in the substantia nigra pars compacta. {ECO:0000269|PubMed:11374880, ECO:0000269|PubMed:11414770, ECO:0000269|PubMed:23690988}.
Top Pathways GABAergic synapse, Regulation of autophagy

Anti-GABARAPL1 antibody - ab94996 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GABARAPL1 antibody (ab94996) at 1/500 dilutionLane 1 : Human SH-SY5Y whole cell lysate - expressing GFPLane 2 : Human SH-SY5Y whole cell lysate - expressing GFP-GABARAPLane 3 : Human SH-SY5Y whole cell lysate - expressing GFP-GABARAPL1Lane 4 : Human SH-SY5Y whole cell lysate - epressing GFP-GABARAPL2Lysates/proteins at 30 µg per lane.SecondaryHRP-conjugated Goat anti-rabbit at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-GABARAPL1 antibody - ab77952 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GABARAPL1 antibody (ab77952) at 1 µg/ml + mouse brain lysate

Anti-GABARAPL1 / ATG8 Antibody (N-Terminus) - LS-C190078 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GABARAPL1 / ATG8 Antibody (AP) - LS-C235503 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GABARAPL1 / ATG8 Antibody (Biotin) - LS-C235504 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GABARAPL1 / ATG8 Antibody (APC) - LS-C235505 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GABARAPL1 / ATG8 Antibody (Azide-free, HRP) - LS-C249030 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GABARAPL1 / ATG8 Antibody (PE) - LS-C235511 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GABARAPL1 / ATG8 Antibody - LS-C321509 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GABARAPL1 / ATG8 Antibody (aa35-84) - LS-C102630 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GABARAPL1 antibody LS-C102630 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.

Anti-GABARAPL1 / ATG8 Antibody (aa31-80) - LS-C201725 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of Human Fetal Brain. GABARAPL1 antibody dilution 1.0 ug/ml.

Anti-GABARAPL1 / ATG8 Antibody - LS-C166314 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with GABARAPL1 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-GABARAPL1 / ATG8 Antibody (N-Terminus) IHC-plus™ - LS-B4021 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GABARAPL1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4021 concentration 5 ug/ml.

Anti-GABARAPL1 / ATG8 Antibody (FITC) - LS-C235506 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

GABARAPL1 Antibody - NBP1-55202 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GABARAPL1 Antibody [NBP1-55202] - Hela Whole Cell lysates, Antibody Dilution: 1.0 ug/ml.

GABARAPL1 Antibody - NBP1-55203 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GABARAPL1 Antibody - NBP2-14032 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GABARAPL1 Antibody [NBP2-14032] Staining of human stomach, upper shows moderate cytoplasmic positivity in glandular cells.

Anti-GABARAPL1 antibody produced in rabbit - HPA051386 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GABARAPL1:<B>Cat. No. HPA051386</B>: Immunohistochemical staining of human stomach, upper shows moderate cytoplasmic positivity in glandular cells.

Anti-GABARAPL1, (N-terminal) antibody produced in rabbit - SAB2103059 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GABARAPL1, (N-terminal): <B>Cat. No. SAB2103059</B>: Immunohistochemistry of GABARAPL1 in Human Brain tissue with GABARAPL1 antibody at 5.0 μg/mL.

Anti-GABARAPL1 antibody produced in rabbit - SAB2103117 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GABARAPL1, antibody produced in rabbit: <B>Cat. No. SAB2103117</B>: Immunoblotting analysis of GABARAPL1 in transfected 293T cell lysate with GABARAPL1 anitbody at 1 μg/mL.

GABARAPL1 antibody - N-terminal region (ARP55398_P050) - ARP55398_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GABARAPL1 antibody - middle region (ARP55399_P050) - ARP55399_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GABARAPL1 Antibody - middle region (ARP58901_P050) - ARP58901_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GABARAPL1-Antibody - AP9133a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of GABARAPL1 Antibody (Cat. #AP9133a) in Hela cell line lysates (35ug/lane). GABARAPL1 (arrow) was detected using the purified Pab.

GABARAPL1 Antibody (OAAB05722) - OAAB05722 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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