EDF1

Gene Symbol	EDF1
Entrez Gene	8721
Alt Symbol	EDF-1, MBF1
Species	Human
Gene Type	protein-coding
Description	endothelial differentiation-related factor 1
Other Description	multiprotein bridging factor 1
Swissprots	Q5T5T2 O60869 Q9UIM1
Accessions	CAJ42711 CBX85963 CBX85993 EAW88296 EAW88297 EAW88298 O60869 AA325420 AB002282 BAA88073 AB002283 BAA88074 BC015500 AAH15500 BI833652 BM800379 BQ279031 BT009863 AAP88865 CR541914 CAG46712 DQ891577 ABM82503 DQ894770 ABM85696 HY029111 HY086994 HY170122 NM_001281297 NP_001268226 NM_001281298 NP_001268227 NM_001281299 NP_001268228 NM_003792 NP_003783 NM_153200 NP_694880
Function	Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism. {ECO:0000269|PubMed:10567391, ECO:0000269|PubMed:12040021, ECO:0000269|PubMed:15112053, ECO:0000269|PubMed:9813014}.
Subcellular Location	Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.
Tissue Specificity	Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues. {ECO:0000269|PubMed:10567391, ECO:0000269|PubMed:12040021, ECO:0000269|PubMed:9813014}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EDF1 / MBF1 Antibody Blocking Peptide - LS-E13785 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EDF1 / MBF1 Antibody Blocking Peptide - LS-E12686 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EDF1 Recombinant Protein - H00008721-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

EDF1 Protein - NBP1-45307 from Novus Biologicals Category Protein Prices $309.00 Sizes 100 µg Species Human

EDF1 Protein (OPPA02292) - OPPA02292 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human EDF1 protein - orb81078 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Species Human

EDF1 protein (His tag) - 80R-1417 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

EDF-1 (1-148, His-tag) - AR09593PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

EDF-1 (1-148, His-tag) - AR09593PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

EDF-1 - H00008721-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

EDF-1 - H00008721-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Endothelial Differentiation-Related Factor 1, Human Recombinant - 228-13094-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Endothelial Differentiation-Related Factor 1 - 228-13094-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Endothelial Differentiation-Related Factor 1 - 228-13094-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

EDF1, 1-148aa, Human, His tag, E.coli - 01-1900-1 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Endothelial Differentiation-Related Factor 1, EDF1, Human, Recombinant - 19-CE12 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source E. coli Species Human

EDF1 fusion protein - Ag3063 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

EDF1 Human - PRPS-501 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 25 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human EDF1 Protein - BP001645-CE12 from Syd Labs Category Protein Prices $180.00, $528.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human EDF1 Protein - BP001645-PRO-494 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 25 µg, 1 mg Source E. coli-derived. Species Human

EDF1 Human Protein - GWB-BSP461 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 25 μg, 1000 μg Source Escherichia Coli. Species Human

EDF1, 1-148aa, Recombinant Protein - GWB-P1383E from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human EDF1, His-tagged - EDF1-2774H from Creative Biomart Category Protein Source E.coli.

Recombinant Human EDF1, His-tagged - EDF1-28461TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human EDF1, GST-tagged - EDF1-12280H from Creative Biomart Category Protein Source E.coli Species Human

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