EDF1

Gene Symbol EDF1
Entrez Gene 8721
Alt Symbol EDF-1, MBF1
Species Human
Gene Type protein-coding
Description endothelial differentiation-related factor 1
Other Description multiprotein bridging factor 1
Swissprots Q5T5T2 O60869 Q9UIM1
Accessions CAJ42711 CBX85963 CBX85993 EAW88296 EAW88297 EAW88298 O60869 AA325420 AB002282 BAA88073 AB002283 BAA88074 BC015500 AAH15500 BI833652 BM800379 BQ279031 BT009863 AAP88865 CR541914 CAG46712 DQ891577 ABM82503 DQ894770 ABM85696 HY029111 HY086994 HY170122 NM_001281297 NP_001268226 NM_001281298 NP_001268227 NM_001281299 NP_001268228 NM_003792 NP_003783 NM_153200 NP_694880
Function Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism. {ECO:0000269|PubMed:10567391, ECO:0000269|PubMed:12040021, ECO:0000269|PubMed:15112053, ECO:0000269|PubMed:9813014}.
Subcellular Location Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.
Tissue Specificity Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues. {ECO:0000269|PubMed:10567391, ECO:0000269|PubMed:12040021, ECO:0000269|PubMed:9813014}.

EDF1 CRISPR/Cas9 KO Plasmid (h) - sc-407217 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 HDR Plasmid (h) - sc-407217-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 Double Nickase Plasmid (h) - sc-407217-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 Double Nickase Plasmid (h2) - sc-407217-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 CRISPR Activation Plasmid (h) - sc-407217-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 CRISPR Activation Plasmid (h2) - sc-407217-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 Lentiviral Activation Particles (h) - sc-407217-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 Lentiviral Activation Particles (h2) - sc-407217-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 siRNA (h) - sc-77227 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EDF1 shRNA Plasmid (h) - sc-77227-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EDF1 shRNA (h) Lentiviral Particles - sc-77227-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EDF1 RNAi - H00008721-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

EDF1 RNAi - H00008721-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU101941 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7654 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7654 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00264 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00264

EDF1 siRNA (Human) - CRH5741 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EDF1 - MBS8240215 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EDF1 (NM_003792.2) - SHH283153 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human EDF1(NM_003792.2) - SHH023627 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human EDF1(NM_153200.1) - SHH023645 from Creative biogene

Category siRNA
Species Reactivities Human

EDF1 CRISPR/Cas9 KO Plasmid (h2) - sc-407217-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDF1 HDR Plasmid (h2) - sc-407217-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human EDF1 siRNA - orb266243 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
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