AGO3

Gene Symbol	AGO3
Entrez Gene	192669
Alt Symbol	EIF2C3
Species	Human
Gene Type	protein-coding
Description	argonaute RISC catalytic component 3
Other Description	argonaute 3|eukaryotic translation initiation factor 2C, 3|hAgo3|protein argonaute-3
Swissprots	B1ALI0 Q5TA55 Q9H1U6 Q9H9G7
Accessions	EAX07394 EAX07395 Q9H9G7 AA251146 AK022827 BAB14262 AK027796 BAB55374 AK292870 BAF85559 AK302289 BAG63629 AK303929 BAG64857 BC025769 BC066888 AAH66888 BC144409 BC156434 AAI56435 BC172480 AAI72480 BF438817 BF979526 BX104163 XM_005270575 XP_005270632 XM_005270576 XP_005270633 XM_011540879 XP_011539181 XM_011540880 XP_011539182 XM_011540881 XP_011539183 XM_011540882 XP_011539184 NM_024852 NP_079128 NM_177422 NP_803171
Function	Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. {ECO:0000255|HAMAP- Rule:MF_03032, ECO:0000269|PubMed:18771919, ECO:0000269|PubMed:23064648}.
Subcellular Location	Cytoplasm, P-body {ECO:0000255|HAMAP- Rule:MF_03032, ECO:0000269|PubMed:16081698}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Argonaute 3 / eIF2C 3 full length protein - ab131912 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Human Argonaute 3 / eIF2C 3 peptide - ab24437 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Argonaute 3 / eIF2C 3 protein fragment - ab153621 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

AGO3 / EIF2C3 Antibody Blocking Peptide - LS-E21520 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AGO3 / EIF2C3 Antibody Blocking Peptide - LS-E21521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Argonaute 3 Protein - H00192669-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human Argonaute 3 Protein - H00192669-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human AGO3 His tag protein - orb84647 from Biorbyt Category Protein Prices $476.00, $638.00 Sizes 10 μg, 20 μg Source Insect Species Human

EIF2C3 Blocking Peptide - 33R-5810 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Eif2c3 Blocking Peptide - 33R-9576 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

EIF2C3 / AGO3 - H00192669-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

EIF2C3 / AGO3 - H00192669-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

EIF2C3 / AGO3 - H00192669-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EIF2C3 fusion protein - ag11483 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

EIF2C3 fusion protein - ag11537 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human EIF2C3, His tagged - EIF2C3-5174H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Human AGO3 / Argonaute 3 / EIF2C3 Protein (His Tag) - 11433-H07B-10 from Sino Biological Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human Protein argonaute-3(EIF2C3) ,partial - CSB-YP875700HU CSB-EP875700HU CSB-BP875700HU CSB-MP875700HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

EIF2C3 / AGO3 (transcript variant 1) - TP322233 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Protein argonaute-3 (EIF2C3), partial, Recombinant Protein - MBS1299601 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human AGO3 / Argonaute 3 / EIF2C3 Protein (His tag) - PKSH031121 from Elabscience Category Protein Source Baculovirus-Insect Cells Species Human

Argonaute 3 Protein - NBP2-13951PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

EIF2C3 Peptide, Human - M34GP04806H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant AGO3 protein - 31523 from ActiveMotif Category Protein Prices $395.00, $3,500.00 Sizes 20 µg, 1 mg Source Baculovirus Species Human

Human AGO3 / Argonaute 3 / EIF2C3 Protein (His Tag) - 11433-H07B from ABclonal Category Protein Prices $158.00, $248.00 Sizes 10 µg, 20 µg Source Baculovirus-Insect Cells Species Human

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