AGO3

Gene Symbol AGO3
Entrez Gene 192669
Alt Symbol EIF2C3
Species Human
Gene Type protein-coding
Description argonaute RISC catalytic component 3
Other Description argonaute 3|eukaryotic translation initiation factor 2C, 3|hAgo3|protein argonaute-3
Swissprots B1ALI0 Q5TA55 Q9H1U6 Q9H9G7
Accessions EAX07394 EAX07395 Q9H9G7 AA251146 AK022827 BAB14262 AK027796 BAB55374 AK292870 BAF85559 AK302289 BAG63629 AK303929 BAG64857 BC025769 BC066888 AAH66888 BC144409 BC156434 AAI56435 BC172480 AAI72480 BF438817 BF979526 BX104163 XM_005270575 XP_005270632 XM_005270576 XP_005270633 XM_011540879 XP_011539181 XM_011540880 XP_011539182 XM_011540881 XP_011539183 XM_011540882 XP_011539184 NM_024852 NP_079128 NM_177422 NP_803171
Function Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. {ECO:0000255|HAMAP- Rule:MF_03032, ECO:0000269|PubMed:18771919, ECO:0000269|PubMed:23064648}.
Subcellular Location Cytoplasm, P-body {ECO:0000255|HAMAP- Rule:MF_03032, ECO:0000269|PubMed:16081698}.

Argonaute 3 (D15D2) Rabbit mAb - 5054 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D15D2
Western blot analysis of extracts from PANC-1, HeLa, and C2C12 cells using Argonaute 3 (D15D2) Rabbit mAb.

eIF2C3 (C-13) - sc-32662 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
eIF2C3 (C-13): sc-32662. Western blot analysis of eIF2C3 expression in F9 whole cell lysate.

eIF2C3 (F-12) - sc-32661 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

eIF2C3 (N-12) - sc-32660 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Argonaute 3 / eIF2C 3 antibody - ab3593 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Rat dorsal root ganglia were fixed in paraformaldehyde, blocked with 2% BSA for 30 minutes then incubated with ab3593 (1/200 dilution). For further details please refer to Hengst U et al  (2006).

Anti-Argonaute 3 / eIF2C 3 antibody - ab94781 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Argonaute 3 / eIF2C 3 antibody (ab94781) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal thymus lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Argonaute 3 / eIF2C 3 antibody - ab115921 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Argonaute 3 / eIF2C 3 antibody (ab115921) at 1 µg/ml + Mouse pancreas lysate at 10 µg

Anti-Argonaute 3 / eIF2C 3 antibody [EPR9576] - ab154844 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9576
All lanes : Anti-Argonaute 3 / eIF2C 3 antibody [EPR9576] (ab154844) at 1/1000 dilutionLane 1 : Human fetal brain lysateLane 2 : Human fetal kidney lysateLysates/proteins at 10 µl/ml buffer per lane.

Anti-Argonaute 3 / eIF2C 3 antibody - Aminoterminal end - ab135067 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Argonaute 3 / eIF2C 3 antibody - Aminoterminal end (ab135067) at 1/1000 dilution + Mouse MEF whole cell lysate

Anti-AGO3 / EIF2C3 Antibody (clone 13A153) - LS-C183368 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 13A153

Anti-AGO3 / EIF2C3 Antibody - LS-C309349 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AGO3 / EIF2C3 Antibody (aa160-209) - LS-C145287 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EIF2C3 / AGO3 antibody LS-C145287 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.

Anti-AGO3 / EIF2C3 Antibody (N-Terminus) - LS-C110926 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EIF2C3 / AGO3 antibody LS-C110926 Western blot of Fetal Thymus lysate.

Argonaute 3 Antibody - NBP1-54932 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Argonaute 3 Antibody [NBP1-54932] - Titration: 0.2-1 ug/ml, Positive Control: Human Thymus.

Argonaute 3 Antibody - H00192669-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Argonaute 3 Antibody [H00192669-A01] - EIF2C3 polyclonal antibody (A01), Lot # 061025JCS1 Western Blot analysis of EIF2C3 expression in MES-SA/Dx5 ( Cat # L021V1 ).

Argonaute 3 Antibody - NBP2-13951 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Argonaute 3 Antibody [NBP2-13951] Staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

Argonaute 3 Antibody - H00192669-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Argonaute 3/eIF2C3 Polyclonal Antibody - bs-12517R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Argonaute 3/eIF2C3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12517R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Argonaute 3/eIF2C3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12517R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Argonaute 3/eIF2C3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12517R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Argonaute 3/eIF2C3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12517R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Argonaute 3/eIF2C3 Polyclonal Antibody, Cy3 Conjugated - bs-12517R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Argonaute 3/eIF2C3 Polyclonal Antibody, Cy5 Conjugated - bs-12517R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Argonaute 3/eIF2C3 Polyclonal Antibody, Cy5.5 Conjugated - bs-12517R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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