AGO3

Gene Symbol AGO3
Entrez Gene 192669
Alt Symbol EIF2C3
Species Human
Gene Type protein-coding
Description argonaute RISC catalytic component 3
Other Description argonaute 3|eukaryotic translation initiation factor 2C, 3|hAgo3|protein argonaute-3
Swissprots B1ALI0 Q5TA55 Q9H1U6 Q9H9G7
Accessions EAX07394 EAX07395 Q9H9G7 AA251146 AK022827 BAB14262 AK027796 BAB55374 AK292870 BAF85559 AK302289 BAG63629 AK303929 BAG64857 BC025769 BC066888 AAH66888 BC144409 BC156434 AAI56435 BC172480 AAI72480 BF438817 BF979526 BX104163 XM_005270575 XP_005270632 XM_005270576 XP_005270633 XM_011540879 XP_011539181 XM_011540880 XP_011539182 XM_011540881 XP_011539183 XM_011540882 XP_011539184 NM_024852 NP_079128 NM_177422 NP_803171
Function Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. {ECO:0000255|HAMAP- Rule:MF_03032, ECO:0000269|PubMed:18771919, ECO:0000269|PubMed:23064648}.
Subcellular Location Cytoplasm, P-body {ECO:0000255|HAMAP- Rule:MF_03032, ECO:0000269|PubMed:16081698}.

eIF2C3 CRISPR/Cas9 KO Plasmid (h) - sc-401908 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C3 HDR Plasmid (h) - sc-401908-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C3 Double Nickase Plasmid (h) - sc-401908-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C3 Double Nickase Plasmid (h2) - sc-401908-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C3 CRISPR Activation Plasmid (h) - sc-401908-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C3 CRISPR Activation Plasmid (h2) - sc-401908-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C3 Lentiviral Activation Particles (h) - sc-401908-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C3 Lentiviral Activation Particles (h2) - sc-401908-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF2C3 siRNA (h) - sc-44410 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF2C3 shRNA Plasmid (h) - sc-44410-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF2C3 shRNA (h) Lentiviral Particles - sc-44410-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Argonaute 3 RNAi - H00192669-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Argonaute 3 RNAi - H00192669-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU101691 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7751 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7751 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AGO3 siRNA (Human) - CRJ6157 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGO3 - MBS8231669 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EIF2C3 (NM_177422.2) - SHH284337 from Creative biogene

Category siRNA
Species Reactivities Human

AGO3 shRNA Plasmid (Human) - CHJ6157 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EIF2C3 miRNA 3'UTR clone - MiUTR3H-09169 from Creative biogene

Species Reactivities Human

EIF2C3 miRNA 3'UTR clone - MiUTR3H-09170 from Creative biogene

Species Reactivities Human
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