| Gene Symbol |
Tlr12
|
| Entrez Gene |
384059
|
| Alt Symbol |
Gm1365, Tlr11
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
toll-like receptor 12
|
| Other Description |
-
|
| Swissprots |
Q6QNU9
|
| Accessions |
EDL30230 Q6QNU9 AK137624 BAE23434 AK143385 BAE25360 AY510705 AAS37673 AY531552 AAS83531 BC131921 AAI31922 NM_205823 NP_991392
|
| Function |
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). Plays a role in preventing infection of internal organs of the urogenital system. {ECO:0000250, ECO:0000269|PubMed:15001781}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Macrophages, liver, kidney and bladder epithelial cells. {ECO:0000269|PubMed:15001781}.
|