Gene Symbol | Tlr12 |
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Entrez Gene | 384059 |
Alt Symbol | Gm1365, Tlr11 |
Species | Mouse |
Gene Type | protein-coding |
Description | toll-like receptor 12 |
Other Description | - |
Swissprots | Q6QNU9 |
Accessions | EDL30230 Q6QNU9 AK137624 BAE23434 AK143385 BAE25360 AY510705 AAS37673 AY531552 AAS83531 BC131921 AAI31922 NM_205823 NP_991392 |
Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). Plays a role in preventing infection of internal organs of the urogenital system. {ECO:0000250, ECO:0000269|PubMed:15001781}. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Macrophages, liver, kidney and bladder epithelial cells. {ECO:0000269|PubMed:15001781}. |
TLR12 CRISPR/Cas9 KO Plasmid (m) - sc-436417 from Santa Cruz Biotechnology
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TLR12 HDR Plasmid (m) - sc-436417-HDR from Santa Cruz Biotechnology
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TLR12 Double Nickase Plasmid (m) - sc-436417-NIC from Santa Cruz Biotechnology
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TLR12 Double Nickase Plasmid (m2) - sc-436417-NIC-2 from Santa Cruz Biotechnology
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TLR12 CRISPR Activation Plasmid (m) - sc-436417-ACT from Santa Cruz Biotechnology
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TLR12 CRISPR Activation Plasmid (m2) - sc-436417-ACT-2 from Santa Cruz Biotechnology
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TLR12 Lentiviral Activation Particles (m) - sc-436417-LAC from Santa Cruz Biotechnology
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TLR12 Lentiviral Activation Particles (m2) - sc-436417-LAC-2 from Santa Cruz Biotechnology
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TLR12 siRNA (m) - sc-154297 from Santa Cruz Biotechnology
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TLR12 shRNA Plasmid (m) - sc-154297-SH from Santa Cruz Biotechnology
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TLR12 shRNA (m) Lentiviral Particles - sc-154297-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN42893 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42893 from Sigma-Aldrich
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TLR12 siRNA (Mouse) - CRN4943 from Cohesion Biosciences
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TLR12 - MBS8232742 from MyBioSource
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shRNA set against Mouse Tlr12 (NM_205823.2) - SHH427948 from Creative biogene
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shRNA set against Mouse Tlr12(NM_205823.2) - SHL072934 from Creative biogene
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Mouse TLR12 siRNA - orb294418 from Biorbyt
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TLR12 shRNA Plasmid (Mouse) - CHN4943 from Cohesion Biosciences
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TLR12 miRNA 3'UTR clone - MiUTR1M-11790 from Creative biogene
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