| Gene Symbol | Tlr12 |
|---|---|
| Entrez Gene | 384059 |
| Alt Symbol | Gm1365, Tlr11 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | toll-like receptor 12 |
| Other Description | - |
| Swissprots | Q6QNU9 |
| Accessions | EDL30230 Q6QNU9 AK137624 BAE23434 AK143385 BAE25360 AY510705 AAS37673 AY531552 AAS83531 BC131921 AAI31922 NM_205823 NP_991392 |
| Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). Plays a role in preventing infection of internal organs of the urogenital system. {ECO:0000250, ECO:0000269|PubMed:15001781}. |
| Subcellular Location | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Tissue Specificity | Macrophages, liver, kidney and bladder epithelial cells. {ECO:0000269|PubMed:15001781}. |
Active mouse TLR11 peptide - ab39867 from Abcam
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Active mouse TLR11 peptide - ab39868 from Abcam
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TLR11 Blocking Peptide - NBP1-77202PEP from Novus Biologicals
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TLR11 Blocking Peptide - NBP1-77204PEP from Novus Biologicals
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Recombinant Mouse TLR12 Fc Chimera, CF - 8086-TR-025 from R&D Systems
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Recombinant Mouse Toll-like receptor 12(Tlr12) - CSB-YP740822MO CSB-EP740822MO CSB-BP740822MO CSB-MP740822MO from Cusabio
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Recombinant Mouse TLR12 Fc Chimera Protein, CF - 8086-TR from R&D Systems
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