Gene Symbol | CYBA |
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Entrez Gene | 1535 |
Alt Symbol | p22-PHOX |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome b-245, alpha polypeptide |
Other Description | cytochrome b light chain|cytochrome b(558) alpha chain|cytochrome b(558) alpha-subunit|cytochrome b, alpha polypeptide|cytochrome b-245 light chain|cytochrome b558 subunit alpha|flavocytochrome b-558 alpha polypeptide|neutrophil cytochrome b 22 kDa polypeptide|p22 phagocyte B-cytochrome|p22phox|superoxide-generating NADPH oxidase light chain subunit |
Swissprots | P13498 Q9BR72 Q14090 |
Accessions | AAM96953 ABF20535 EAW66793 EAW66794 EAW66795 EAW66796 P13498 AK097127 AK125578 AK300049 BAG61858 AK309030 BC006465 AAH06465 BC011565 BC028224 BC033739 BT006861 AAP35507 BX109994 DQ893235 ABM84161 DQ896565 ABM87564 M21186 AAA90925 XM_011522905 XP_011521207 NM_000101 NP_000092 |
Function | Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. {ECO:0000269|PubMed:15824103}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:15585859, ECO:0000269|PubMed:22808130}. |
Top Pathways | Leukocyte transendothelial migration, Leishmaniasis, Phagosome, Osteoclast differentiation |
p22-phox (E-11) - sc-271968 from Santa Cruz Biotechnology
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p22-phox (CS9) - sc-130551 from Santa Cruz Biotechnology
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p22-phox (E-8) - sc-271262 from Santa Cruz Biotechnology
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p22-phox (C-18)-R - sc-27634-R from Santa Cruz Biotechnology
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p22-phox (FL-195) - sc-20781 from Santa Cruz Biotechnology
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p22-phox (44.1) - sc-130550 from Santa Cruz Biotechnology
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p22-phox (C-17) - sc-11712 from Santa Cruz Biotechnology
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Anti-Cytochrome b245 Light Chain antibody - ab75941 from Abcam
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Anti-Cytochrome b245 Light Chain antibody - ab191512 from Abcam
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Anti-Cytochrome b245 Light Chain antibody [44.1] - ab80896 from Abcam
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Anti-Cytochrome b245 Light Chain antibody [CS9] - ab87736 from Abcam
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Anti-CYBA / p22phox Antibody (clone CS9, FITC) - LS-C185313 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa124-153, AP) - LS-C208729 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa124-153, FITC) - LS-C208732 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa124-153, APC) - LS-C208730 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa124-153, Biotin) - LS-C208731 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa124-153, Azide-free, HRP) - LS-C208733 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa107-156) - LS-C110868 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa124-153, PE) - LS-C208734 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa124-153) - LS-C320708 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody (aa124-153) - LS-C167196 from LifeSpan Bioscience
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Anti-CYBA / p22phox Antibody - LS-C341067 from LifeSpan Bioscience
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Cytochrome b245 alpha Antibody - NBP1-59573 from Novus Biologicals
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Cytochrome b245 alpha Antibody (CS9) - NBP1-40974 from Novus Biologicals
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Cytochrome b245 alpha Antibody (CS9) [DyLight 350] - NBP1-40974UV from Novus Biologicals
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