Gene Symbol | SIGLEC6 |
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Entrez Gene | 946 |
Alt Symbol | CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1 |
Species | Human |
Gene Type | protein-coding |
Description | sialic acid binding Ig-like lectin 6 |
Other Description | CD33 antigen-like 1|obesity-binding protein 1|sialic acid-binding Ig-like lectin 6 |
Swissprots | B2RTS8 O15388 C9JBE5 A8MV71 O43700 O43699 F8WA78 |
Accessions | AAK83655 EAW72024 EAW72025 EAW72026 EAW72027 O43699 AK300170 BAG61951 AK300182 BAG61961 AK308174 AK309903 AU138048 BC035359 AAH35359 BC140798 AAI40799 CA495365 D86358 BAA24983 D86359 BAA24984 U71382 AAB70702 XM_011527533 XP_011525835 XM_011527534 XP_011525836 XM_011527535 XP_011525837 XM_011527536 XP_011525838 XM_011527537 XP_011525839 XM_011527538 XP_011525840 XM_011527539 XP_011525841 XR_935876 XR_935877 NM_001177547 NP_001171018 NM_001177548 NP_001171019 NM_001177549 NP_001171020 NM_001245 NP_001236 NM_198845 NP_942142 NM_198846 NP_942143 |
Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. |
Siglec-6 (N-15) - sc-51427 from Santa Cruz Biotechnology
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Siglec-6 (S-18) - sc-51428 from Santa Cruz Biotechnology
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Anti-SIGLEC6 antibody - ab38581 from Abcam
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Anti-SIGLEC6 antibody - ab199105 from Abcam
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Anti-SIGLEC6 antibody - ab167549 from Abcam
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Anti-SIGLEC6 antibody - ab104930 from Abcam
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Anti-SIGLEC6 antibody [MM0907-42P40] - ab201663 from Abcam
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Anti-SIGLEC6 antibody - N-terminal - ab172928 from Abcam
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Anti-SIGLEC6 Antibody (N-Terminus, FITC) - LS-C282723 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (N-Terminus, Biotin) - LS-C282722 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (N-Terminus, APC) - LS-C282724 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (N-Terminus, Azide-free, HRP) - LS-C282725 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (C-Terminus, APC) - LS-C282726 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (N-Terminus, PE) - LS-C282727 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (C-Terminus, Biotin) - LS-C282728 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (aa180-229) - LS-C82454 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (C-Terminus, AP) - LS-C282729 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (aa74-123) - LS-C80471 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (C-Terminus, FITC) - LS-C282731 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (N-Terminus) - LS-C82448 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (C-Terminus) - LS-C80472 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (C-Terminus, PE) - LS-C282732 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (C-Terminus, Azide-free, HRP) - LS-C282733 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (aa10-40) - LS-C97827 from LifeSpan Bioscience
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Anti-SIGLEC6 Antibody (clone 2G6) - LS-C196855 from LifeSpan Bioscience
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