SIGLEC6

Gene Symbol	SIGLEC6
Entrez Gene	946
Alt Symbol	CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1
Species	Human
Gene Type	protein-coding
Description	sialic acid binding Ig-like lectin 6
Other Description	CD33 antigen-like 1|obesity-binding protein 1|sialic acid-binding Ig-like lectin 6
Swissprots	B2RTS8 O15388 C9JBE5 A8MV71 O43700 O43699 F8WA78
Accessions	AAK83655 EAW72024 EAW72025 EAW72026 EAW72027 O43699 AK300170 BAG61951 AK300182 BAG61961 AK308174 AK309903 AU138048 BC035359 AAH35359 BC140798 AAI40799 CA495365 D86358 BAA24983 D86359 BAA24984 U71382 AAB70702 XM_011527533 XP_011525835 XM_011527534 XP_011525836 XM_011527535 XP_011525837 XM_011527536 XP_011525838 XM_011527537 XP_011525839 XM_011527538 XP_011525840 XM_011527539 XP_011525841 XR_935876 XR_935877 NM_001177547 NP_001171018 NM_001177548 NP_001171019 NM_001177549 NP_001171020 NM_001245 NP_001236 NM_198845 NP_942142 NM_198846 NP_942143
Function	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Siglec-6 CRISPR/Cas9 KO Plasmid (h) - sc-416316 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Siglec-6 HDR Plasmid (h) - sc-416316-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siglec-6 Double Nickase Plasmid (h) - sc-416316-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siglec-6 Double Nickase Plasmid (h2) - sc-416316-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siglec-6 CRISPR Activation Plasmid (h) - sc-416316-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Siglec-6 CRISPR Activation Plasmid (h2) - sc-416316-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Siglec-6 Lentiviral Activation Particles (h) - sc-416316-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siglec-6 Lentiviral Activation Particles (h2) - sc-416316-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siglec-6 siRNA (h) - sc-72251 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Siglec-6 shRNA Plasmid (h) - sc-72251-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Siglec-6 shRNA (h) Lentiviral Particles - sc-72251-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Siglec-6/CD327 RNAi - H00000946-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Siglec-6/CD327 RNAi - H00000946-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Siglec-6/CD327 RNAi - H00000946-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU081651 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU077211 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19334 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19334 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

SIGLEC6 siRNA (Human) - CRH0668 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SIGLEC6 - MBS8211050 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human SIGLEC6 (NM_001245.5) - SHH407476 from Creative biogene Category siRNA Species Reactivities Human

Human SIGLEC6 siRNA - orb261170 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SIGLEC6 shRNA Plasmid (Human) - CHH0668 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

SIGLEC6 miRNA 3'UTR clone - MiUTR3H-06775 from Creative biogene Species Reactivities Human

SIGLEC6 miRNA 3'UTR clone - MiUTR3H-06776 from Creative biogene Species Reactivities Human

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