Gene Symbol | SIGLEC6 |
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Entrez Gene | 946 |
Alt Symbol | CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1 |
Species | Human |
Gene Type | protein-coding |
Description | sialic acid binding Ig-like lectin 6 |
Other Description | CD33 antigen-like 1|obesity-binding protein 1|sialic acid-binding Ig-like lectin 6 |
Swissprots | B2RTS8 O15388 C9JBE5 A8MV71 O43700 O43699 F8WA78 |
Accessions | AAK83655 EAW72024 EAW72025 EAW72026 EAW72027 O43699 AK300170 BAG61951 AK300182 BAG61961 AK308174 AK309903 AU138048 BC035359 AAH35359 BC140798 AAI40799 CA495365 D86358 BAA24983 D86359 BAA24984 U71382 AAB70702 XM_011527533 XP_011525835 XM_011527534 XP_011525836 XM_011527535 XP_011525837 XM_011527536 XP_011525838 XM_011527537 XP_011525839 XM_011527538 XP_011525840 XM_011527539 XP_011525841 XR_935876 XR_935877 NM_001177547 NP_001171018 NM_001177548 NP_001171019 NM_001177549 NP_001171020 NM_001245 NP_001236 NM_198845 NP_942142 NM_198846 NP_942143 |
Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. |
Active human SIGLEC6 protein fragment - ab182674 from Abcam
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Human SIGLEC6 full length protein - ab158055 from Abcam
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Human SIGLEC6 protein fragment - ab158056 from Abcam
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SIGLEC6 Antibody Blocking Peptide - LS-E4023 from LifeSpan Bioscience
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SIGLEC6 Antibody Blocking Peptide - LS-E4024 from LifeSpan Bioscience
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SIGLEC6 Antibody Blocking Peptide - LS-E27438 from LifeSpan Bioscience
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SIGLEC6 Antibody Blocking Peptide - LS-E15738 from LifeSpan Bioscience
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SIGLEC6 Antibody Blocking Peptide - LS-E15432 from LifeSpan Bioscience
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SIGLEC6 Antibody Blocking Peptide - LS-E15433 from LifeSpan Bioscience
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SIGLEC6 Antibody Blocking Peptide - LS-E15434 from LifeSpan Bioscience
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Recombinant Human Siglec-6/CD327 Protein - H00000946-Q01 from Novus Biologicals
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Recombinant Human Siglec-6/CD327 Protein - H00000946-P01 from Novus Biologicals
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Siglec-6/CD327 Recombinant Protein - H00000946-G01 from Novus Biologicals
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Siglec-6/CD327 Peptide - P0598 from Novus Biologicals
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Siglec-6/CD327 Peptide - P0597 from Novus Biologicals
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SIGLEC6-Antibody-C-term-Blocking-Peptide - BP1624b from Abgent, a WuXi AppTec company
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SIGLEC6-Antibody-N-term-Blocking-Peptide - BP1624a from Abgent, a WuXi AppTec company
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SIGLEC6 blocking peptide - GTX88051-PEP from GeneTex
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Recombinant Human Siglec-6/CD327 Fc Chimera, CF - 2859-SL-050 from R&D Systems
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Human SIGLEC6 protein - orb139658 from Biorbyt
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SIGLEC6 Blocking Peptide - 33R-6326 from Fitzgerald
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SIGLEC6 Blocking Peptide - 33R-4208 from Fitzgerald
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SIGLEC6 Blocking Peptide - 33R-3084 from Fitzgerald
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SIGLEC6 Blocking Peptide - 33R-9741 from Fitzgerald
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SIGLEC6 Peptide - AC21-2263-P from Abcore
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