APBA1

Gene Symbol APBA1
Entrez Gene 320
Alt Symbol D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA
Species Human
Gene Type protein-coding
Description amyloid beta (A4) precursor protein-binding, family A, member 1
Other Description adapter protein X11alpha|adaptor protein X11alpha|amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)|amyloid beta A4 precursor protein-binding family A member 1|mint-1|neuron-specific X11 protein|neuronal munc18-1-interacting protein 1|phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Swissprots Q02410 O14914 Q5VYR8 O60570
Accessions EAW62486 EAW62487 Q02410 AF029106 AAC05304 AF047347 AAC39766 AL713639 BC156047 AAI56048 BC157030 AAI57031 BF435835 BQ269294 DA179202 DA313538 L04953 AAA61307 XM_005251968 XP_005252025 XM_006717093 XP_006717156 XM_011518617 XP_011516919 NM_001163 NP_001154
Function Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20531236}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:20531236}. Nucleus {ECO:0000269|PubMed:20531236}. Note=Only about 5% of the protein is located in the nucleus.
Tissue Specificity Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen. {ECO:0000269|PubMed:23737971}.

Panoply™ Human APBA1 Knockdown Stable Cell Line - CSC-DC000738 from Creative biogene

Category Cell Line
Species Human
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