APBA1

Gene Symbol APBA1
Entrez Gene 320
Alt Symbol D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA
Species Human
Gene Type protein-coding
Description amyloid beta (A4) precursor protein-binding, family A, member 1
Other Description adapter protein X11alpha|adaptor protein X11alpha|amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)|amyloid beta A4 precursor protein-binding family A member 1|mint-1|neuron-specific X11 protein|neuronal munc18-1-interacting protein 1|phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Swissprots Q02410 O14914 Q5VYR8 O60570
Accessions EAW62486 EAW62487 Q02410 AF029106 AAC05304 AF047347 AAC39766 AL713639 BC156047 AAI56048 BC157030 AAI57031 BF435835 BQ269294 DA179202 DA313538 L04953 AAA61307 XM_005251968 XP_005252025 XM_006717093 XP_006717156 XM_011518617 XP_011516919 NM_001163 NP_001154
Function Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20531236}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:20531236}. Nucleus {ECO:0000269|PubMed:20531236}. Note=Only about 5% of the protein is located in the nucleus.
Tissue Specificity Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen. {ECO:0000269|PubMed:23737971}.

X11α CRISPR/Cas9 KO Plasmid (h) - sc-405297 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

X11α HDR Plasmid (h) - sc-405297-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

X11α Double Nickase Plasmid (h) - sc-405297-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

X11α Double Nickase Plasmid (h2) - sc-405297-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

X11α CRISPR Activation Plasmid (h) - sc-405297-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

X11α CRISPR Activation Plasmid (h2) - sc-405297-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

X11α Lentiviral Activation Particles (h) - sc-405297-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

X11α Lentiviral Activation Particles (h2) - sc-405297-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

X11α siRNA (h) - sc-36851 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

X11α shRNA Plasmid (h) - sc-36851-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

X11α shRNA (h) Lentiviral Particles - sc-36851-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU129621 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3304 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3304 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08091 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08091

APBA1 siRNA (Human) - CRH0221 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APBA1 - MBS8223093 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human APBA1 (NM_001163.3) - SHH238018 from Creative biogene

Category siRNA
Species Reactivities Human

Human APBA1 siRNA - orb260723 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APBA1 shRNA Plasmid (Human) - CHH0221 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

APBA1 miRNA 3'UTR clone - MiUTR4H-TG00391 from Creative biogene

Species Reactivities Human
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