Gene Symbol | APBA1 |
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Entrez Gene | 320 |
Alt Symbol | D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA |
Species | Human |
Gene Type | protein-coding |
Description | amyloid beta (A4) precursor protein-binding, family A, member 1 |
Other Description | adapter protein X11alpha|adaptor protein X11alpha|amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)|amyloid beta A4 precursor protein-binding family A member 1|mint-1|neuron-specific X11 protein|neuronal munc18-1-interacting protein 1|phosphotyrosine-binding/-interacting domain (PTB)-bearing protein |
Swissprots | Q02410 O14914 Q5VYR8 O60570 |
Accessions | EAW62486 EAW62487 Q02410 AF029106 AAC05304 AF047347 AAC39766 AL713639 BC156047 AAI56048 BC157030 AAI57031 BF435835 BQ269294 DA179202 DA313538 L04953 AAA61307 XM_005251968 XP_005252025 XM_006717093 XP_006717156 XM_011518617 XP_011516919 NM_001163 NP_001154 |
Function | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20531236}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:20531236}. Nucleus {ECO:0000269|PubMed:20531236}. Note=Only about 5% of the protein is located in the nucleus. |
Tissue Specificity | Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen. {ECO:0000269|PubMed:23737971}. |
APBA1 peptide - ab4980 from Abcam
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APBA1 / MINT1 Antibody Blocking Peptide - LS-E10677 from LifeSpan Bioscience
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APBA1 / MINT1 Antibody Blocking Peptide - LS-E31294 from LifeSpan Bioscience
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APBA1 / MINT1 Antibody Blocking Peptide - LS-E26322 from LifeSpan Bioscience
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APBA1 / MINT1 Antibody Blocking Peptide - LS-E30503 from LifeSpan Bioscience
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APBA1/MINT1 blocking peptide - GTX89063-PEP from GeneTex
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APBA1 Blocking Peptide - 33R-7273 from Fitzgerald
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APBA1 Peptide - AC21-1157-P from Abcore
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APBA1 / MINT1 (N-term) Control Peptide - AP55509CP-N from Acris Antibodies
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APBA1 Peptide - 45-260P from ProSci
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APBA1 Peptide - 6925P from ProSci
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Recombinant Amyloid Beta Precursor Protein Binding Protein A2 (APBA2) - RPC957Hu01 from Cloud-clone
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APBA1/MINT1, Peptide - MBS426739 from MyBioSource
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APBA1 Protein - NBP1-84306PEP from Novus Biologicals
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APBA1-Antibody-Center-Blocking-Peptide - BP8593c from Abgent, a WuXi AppTec company
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APBA1 Peptide, Human - M34GP00738H from Creative Peptides
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APBA1 Recombinant Protein Antigen - NBP2-56155PEP from Novus Biologicals
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