FBXO2

Gene Symbol	FBXO2
Entrez Gene	26232
Alt Symbol	FBG1, FBX2, Fbs1, NFB42, OCP1
Species	Human
Gene Type	protein-coding
Description	F-box protein 2
Other Description	F-box gene 1|F-box only protein 2|organ of Corti protein 1
Swissprots	Q6FGJ7 Q9UK22 Q5TGY0 B2R7K7 Q8TB29 Q9UKC6
Accessions	EAW71689 Q9UK22 AF174594 AAF04515 AF187318 AAF01822 AK308531 AK313019 BAG35854 AW138262 AW162121 BC014957 BC025233 AAH25233 BC096747 AAH96747 BE464909 BF967195 BM128229 BP209877 CR542110 CAG46907 DQ892848 ABM83774 DQ892849 ABM83775 DQ896095 ABM87094 H18283 NM_012168 NP_036300
Function	Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Microsome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Top Pathways	Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FBXO2 (A-12) - sc-393873 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

FBXO2 (E-9) - sc-398111 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

FBXO2 (D-19) - sc-69400 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FBXO2 (G-15) - sc-69401 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FBXO2 (H-48) - sc-366922 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-FBXO2 antibody - ab96391 from Abcam Prices $370.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 antibody [EPR7328(2)] - ab133717 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7328(2)

Anti-FBXO2 Antibody - LS-C152917 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-FBXO2 Antibody (C-Terminus) - LS-C146329 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody - LS-C152804 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody - LS-C152805 from LifeSpan Bioscience Prices $365.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (aa141-190) - LS-C205727 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (aa244-271, AP) - LS-C257109 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (aa244-271, APC) - LS-C257110 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (aa244-271, Biotin) - LS-C257111 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (aa244-271, Azide-free, HRP) - LS-C257113 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (aa244-271, PE) - LS-C257114 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (aa244-271, FITC) - LS-C257112 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody - LS-C307498 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-FBXO2 Antibody - LS-C307500 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-FBXO2 Antibody (aa251-279) - LS-C321315 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (Internal, clone EPR7328(2)) - LS-C154650 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7328(2)

Anti-FBXO2 Antibody (aa244-271) - LS-C166080 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-FBXO2 Antibody (aa234-296) - LS-C185664 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

FBXO2 Antibody - H00026232-B01 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Search more