FBXO2

Gene Symbol	FBXO2
Entrez Gene	26232
Alt Symbol	FBG1, FBX2, Fbs1, NFB42, OCP1
Species	Human
Gene Type	protein-coding
Description	F-box protein 2
Other Description	F-box gene 1|F-box only protein 2|organ of Corti protein 1
Swissprots	Q6FGJ7 Q9UK22 Q5TGY0 B2R7K7 Q8TB29 Q9UKC6
Accessions	EAW71689 Q9UK22 AF174594 AAF04515 AF187318 AAF01822 AK308531 AK313019 BAG35854 AW138262 AW162121 BC014957 BC025233 AAH25233 BC096747 AAH96747 BE464909 BF967195 BM128229 BP209877 CR542110 CAG46907 DQ892848 ABM83774 DQ892849 ABM83775 DQ896095 ABM87094 H18283 NM_012168 NP_036300
Function	Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Microsome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Top Pathways	Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FBXO2 full length protein - ab161936 from Abcam Category Protein Source Wheat germ Species Human

Human FBXO2 full length protein - ab180282 from Abcam Category Protein Source E. coli Species Human

FBXO2 Antibody Blocking Peptide - LS-E111 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXO2 Antibody Blocking Peptide - LS-E15871 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXO2 Recombinant Protein - H00026232-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

FBXO2-Antibody-C-term-Blocking-peptide - BP10212b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FBXO2 protein (His tag) - 80R-3885 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

FBXO2 (1-296, His-tag) - AR51572PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

FBXO2 (1-296, His-tag) - AR51572PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

FBXO2 - H00026232-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FBXO2 - H00026232-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FBXO2, 1-296aa, Human, His tag, E.coli - 01-P2752 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

FBXO2 fusion protein - Ag6122 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

FBXO2 fusion protein - Ag6368 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human FBXO2, GST-tagged - FBXO2-12788H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human FBXO2, His-tagged - FBXO2-259H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human F-box only protein 2(FBXO2) - CSB-YP892326HU CSB-EP892326HU CSB-BP892326HU CSB-MP892326HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FBXO2, 1-296aa, Human, His tag, E.coli - ATGP2752 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

FBXO2 - TP310500 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Human FBXO2 protein - orb259893 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 2 μg, 10 μg Species Human

FBXO2 Peptide, Human - M34GP05590H from Creative Peptides Category Peptide Source Synthetic. Species Human

F-box only protein 2 (FBXO2), Recombinant Protein - MBS1334273 from MyBioSource Category Protein Prices $1,050.00, $1,050.00, $1,280.00, $1,280.00, $1,640.00, $1,640.00, $2,105.00, $2,105.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

F-Box Protein 2, Recombinant Protein - MBS145910 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg

FBXO2, Recombinant Protein - MBS205630 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 50 µg, 250 µg Source E Coli Species Human

Recombinant Human FBXO2 Protein - NBP2-51764 from Novus Biologicals Category Protein Prices $259.00, $759.00 Sizes 50 µg, 250 µg Source E. coli Species Human

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