FBXO2

Gene Symbol	FBXO2
Entrez Gene	26232
Alt Symbol	FBG1, FBX2, Fbs1, NFB42, OCP1
Species	Human
Gene Type	protein-coding
Description	F-box protein 2
Other Description	F-box gene 1|F-box only protein 2|organ of Corti protein 1
Swissprots	Q6FGJ7 Q9UK22 Q5TGY0 B2R7K7 Q8TB29 Q9UKC6
Accessions	EAW71689 Q9UK22 AF174594 AAF04515 AF187318 AAF01822 AK308531 AK313019 BAG35854 AW138262 AW162121 BC014957 BC025233 AAH25233 BC096747 AAH96747 BE464909 BF967195 BM128229 BP209877 CR542110 CAG46907 DQ892848 ABM83774 DQ892849 ABM83775 DQ896095 ABM87094 H18283 NM_012168 NP_036300
Function	Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Microsome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Top Pathways	Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

F-box only protein 2 (FBXO2), Human, ELISA Kit - E01F0281 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

FBXO2, F-Box Protein 2, Human, ELISA Kit - E-EL-H0877 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10

F-Box Protein 2, FBXO2, Mouse, ELISA Kit - E-EL-M0489 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

FBXO2, F-Box Protein 2, Rabbit, ELISA Kit - E-EL-RB1711 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

FBXO2, F-Box Protein 2, Chicken, ELISA Kit - E-EL-Ch1423 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

FBXO2, F-Box Protein 2, Porcine, ELISA Kit - E-EL-P0972 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

FBXO2, F-Box Protein 2, Sheep, ELISA Kit - E-EL-S0702 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

FBXO2, F-Box Protein 2, Guinea Pig, ELISA Kit - E-EL-GP0142 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

FBXO2, F-Box Protein 2, Monkey, ELISA Kit - E-EL-MK1918 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human FBXO2 ELISA Kit - HF0069 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine FBXO2 ELISA Kit - AF0069 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

F box only protein 2 (FBXO2), ELISA Kit - MBS7214637 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F Box Protein 2, ELISA Kit - MBS722463 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box Protein 2, ELISA Kit - MBS2506755 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

F-Box Protein 2, ELISA Kit - MBS068100 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box Protein 2, ELISA Kit - MBS096004 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box Protein 2, ELISA Kit - MBS729112 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box Protein 2, ELISA Kit - MBS042014 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box Protein 2, ELISA Kit - MBS2509090 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

F-Box Protein 2, ELISA Kit - MBS046370 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box Protein 2, ELISA Kit - MBS724260 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box Protein 2, ELISA Kit - MBS005924 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

F-Box Protein 2, ELISA Kit - MBS2503207 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

F-Box Protein 2, ELISA Kit - MBS2506279 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

F-Box Protein 2, ELISA Kit - MBS040232 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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