NKX2-2

Gene Symbol NKX2-2
Entrez Gene 4821
Alt Symbol NKX2.2, NKX2B
Species Human
Gene Type protein-coding
Description NK2 homeobox 2
Other Description NK-2 homolog B|NK2 transcription factor related, locus 2|NK2 transcription factor-like protein B|homeobox protein NK-2 homolog B|homeobox protein Nkx-2.2
Swissprots O95096
Accessions AAC83132 AAG16976 EAX10183 O95096 BC075092 AAH75092 BC075093 AAH75093 BM314196 BQ632044 BU070383 CA772329 EU446641 ABZ92170 XM_006723566 XP_006723629 XM_011529237 XP_011527539 XR_937076 XR_937077 XR_937078 XR_937079 NM_002509 NP_002500
Function Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Top Pathways Maturity onset diabetes of the young

NKX2.2 Antibody - 12310 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293 cells, mock transfected (-) or transfected with a construct expressing Myc/DDK-tagged full-length human NKX2.2 (hNKX2.2-Myc/DDK; +), using NKX2.2 Antibody (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

Nkx-2.2 (D-4) - sc-398951 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nkx-2.2 (D-4): sc-398951. Western blot analysis of Nkx-2.2 expression in non-transfected: sc-117752 (A) and human Nkx-2.2 transfected: sc-369812 (B) 293T whole cell lysates.

Nkx-2.2 (F-2) - sc-514161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nkx-2.2 (F-2): sc-514161. Western blot analysis of Nkx-2.2 expression in non-transfected: sc-117752 (A) and human Nkx-2.2 transfected: sc-369812 (B) 293T whole cell lysates.

Nkx-2.2 (H-60) - sc-25404 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nkx-2.2 (H-60): sc-25404. Western blot analysis of Nkx-2.2 expression in mouse brain tissue extract.

Nkx-2.2 (P-20) - sc-15015 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nkx-2.2 (P-20): sc-15015. Western blot analysis of Nkx-2.2 expression in RAW 264.7 (A) and NIH/3T3 (B) nuclear extracts and mouse brain tissue extract (C).

Anti-Nkx2.2 antibody - ab86024 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Nkx2.2 antibody (ab86024) at 1/1000 dilutionLane 1 : An uninduced (negative control) culture of E.coliLane 2 : An induced culture of E.coliSecondaryAnti-Rabbit IgG HRP at 1/1000 dilution

Anti-Nkx2.2 antibody [3E4] - ab129358 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E4
Anti-Nkx2.2 antibody [3E4] (ab129358) at 1/500 dilution + Nkx2.2 recombinant protein

Anti-Nkx2.2 antibody [EPR14638] - N-terminal - ab191077 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14638
Immunofluorescent analysis of 4% paraformaldehyde-fixed C6 cells labeling Nkx2.2 with ab191077 at 1/50, Goat anti rabbit IgG (Alexa Fluor® 555) at 1/200 and DAPI staining (blue). Negative controls also shown.

Anti-Nkx2.2 antibody [NX2/294] - ab187375 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone NX2/294
Immunohistochemical analysis of paraffin embedded Human pancreas tissue labeling Nkx2.2 with ab187375 at 1 µg/ml.

Anti-Nkx2.2 antibody [PR-1C11] - ab98126 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone PR-1C11
Lane 1 : Anti-Nkx2.2 antibody [PR-1C11] (ab98126) at 0.1 µg/mlLanes 2 - 4 : Anti-Nkx2.2 antibody [PR-1C11] (ab98126) at 1 µg/mlLane 1 : Immunogen (Recombinant fragment: amino acids 1-127) at 0.25 µgLane 2 : Immunogen (Recombinant fragment: amino acids 1-127) at 0.25 µgLane 3 : Untransfected HEK 293 cell lysate at 5 µgLane 4 : Nkx2.2 transfected HEK 293 cell lysate at 5 µg

Anti-Nkx2.2 antibody [PR-3B2] - ab98125 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone PR-3B2
Lane 1 : Anti-Nkx2.2 antibody [PR-3B2] (ab98125) at 0.1 µg/mlLanes 2 - 4 : Anti-Nkx2.2 antibody [PR-3B2] (ab98125) at 1 µg/mlLane 1 : Immunogen (Recombinant fragment amino acids 1-127) at 0.25 µgLane 2 : Immunogen (Recombinant fragment amino acids 1-127) at 0.25 µgLane 3 : Untransfected HEK 293 cell lysate at 5 µgLane 4 : Nkx2.2 transfected HEK 293 cell lysate at 5 µg

NKX2.2 Antibody - NBP1-82554 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NKX2.2 Antibody [NBP1-82554] - Analysis in human cell line U-138 MG.

NKX2.2 Antibody (883411) - MAB8167 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 883411
Western blot shows lysates of A‑673 human Ewing's sarcoma cell line and beta TC‑6 mouse beta cell insulinoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human/Mouse/Rat NKX2.2 Monoclonal Antibody (Catalog # MAB8167) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for NKX2.2 at approximately 35 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

NKX2.2 Antibody (SPM564) - NBP2-32884 from Novus Biologicals

Prices $129.00, $299.00, $429.00
Sizes 20 µg, 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone SPM564
Immunohistochemistry-Paraffin: NKX2.2 Antibody (SPM564) [NBP2-32884] - Formalin-fixed, paraffin-embedded human pancreas stained with NKX2.2 Monoclonal Antibody (SPM564).

NKX2.2 Antibody (NX2/294) - NBP2-29432 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone NX2/294
Immunohistochemistry-Paraffin: NKX2.2 Antibody (NX2/294) [NBP2-29432] - Formalin-paraffin pancreas stained with NKX2.2 Ab(NX2/294).

NKX2.2 Antibody (3E4) - NBP2-37486 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E4
Western Blot: NKX2.2 Antibody (3E4) [NBP2-37486] - Western blot analysis using NKX2.2 mAb against human NKX2.2 recombinant protein.(Expected MW is 22 kDa)

NKX2.2 Antibody - NBP2-19546 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Nkx2.2 Antibody [NBP2-19546] - Sample (30 ug of whole cell lysate) A: MCF-7 12% SDS PAGE gel, diluted at 1:1000.

NKX2.2 Antibody (SPM564) [PerCP] - NBP2-34799PCP from Novus Biologicals

Prices $389.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone SPM564

NKX2.2 Antibody (SPM564) [DyLight 755] - NBP2-34799IR from Novus Biologicals

Prices $369.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone SPM564

NKX2.2 Antibody (SPM564) [HRP] - NBP2-34799H from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone SPM564

NKX2.2 Antibody (SPM564) [DyLight 488] - NBP2-34799G from Novus Biologicals

Prices $369.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone SPM564

NKX2.2 Antibody (SPM564) [DyLight 680] - NBP2-34799FR from Novus Biologicals

Prices $369.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone SPM564

NKX2.2 Antibody (SPM564) [DyLight 650] - NBP2-34799C from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone SPM564

NKX2.2 Antibody (SPM564) [Biotin] - NBP2-34799B from Novus Biologicals

Prices $309.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone SPM564

NKX2.2 Antibody (SPM564) [Allophycocyanin] - NBP2-34799APC from Novus Biologicals

Prices $389.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone SPM564
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