NKX2-2

Gene Symbol	NKX2-2
Entrez Gene	4821
Alt Symbol	NKX2.2, NKX2B
Species	Human
Gene Type	protein-coding
Description	NK2 homeobox 2
Other Description	NK-2 homolog B|NK2 transcription factor related, locus 2|NK2 transcription factor-like protein B|homeobox protein NK-2 homolog B|homeobox protein Nkx-2.2
Swissprots	O95096
Accessions	AAC83132 AAG16976 EAX10183 O95096 BC075092 AAH75092 BC075093 AAH75093 BM314196 BQ632044 BU070383 CA772329 EU446641 ABZ92170 XM_006723566 XP_006723629 XM_011529237 XP_011527539 XR_937076 XR_937077 XR_937078 XR_937079 NM_002509 NP_002500
Function	Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Top Pathways	Maturity onset diabetes of the young

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human Nkx2.2 protein fragment - ab152573 from Abcam Category Protein Source Wheat germ Species Human

NKX2-2 Antibody Blocking Peptide - LS-E1895 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NKX2-2 Antibody Blocking Peptide - LS-E11311 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NKX2-2 Antibody Blocking Peptide - LS-E13316 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NKX2-2 Antibody Blocking Peptide - LS-E31237 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human NKX2.2 Protein - H00004821-Q01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

NKX2-2-Antibody-Center-Blocking-peptide - BP12730c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NKX2-2 - H00004821-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NKX2-2 - H00004821-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NKX2-2 (Center) Control Peptide - AP55626CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

NKX2-2 Peptide - 6743P from ProSci Category Peptide Species Human

NKX2-2 fusion protein - Ag4069 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NKX2-2 fusion protein - Ag14462 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human NKX2-2, GST-tagged - NKX2-2-1303H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Homeobox protein Nkx-2.2(NKX2-2) - CSB-YP015842HU CSB-EP015842HU CSB-BP015842HU CSB-MP015842HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NKX2-2 (full length, N-term HIS tag) - TP760219 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

NKX2-2 Peptide, Human - M34GP10410H from Creative Peptides Category Peptide Source Synthetic. Species Human

NKX2.2 Recombinant Protein Antigen - NBP1-82554PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Homeobox protein Nkx-2.2 (NKX2-2), Recombinant Protein - MBS1155190 from MyBioSource Category Protein Prices $1,025.00, $1,025.00, $1,255.00, $1,255.00, $1,585.00, $1,585.00, $2,050.00, $2,050.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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