PEA15

Gene Symbol	PEA15
Entrez Gene	8682
Alt Symbol	HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED
Species	Human
Gene Type	protein-coding
Description	phosphoprotein enriched in astrocytes 15
Other Description	15 kDa phosphoprotein enriched in astrocytes|astrocytic phosphoprotein PEA-15|homolog of mouse MAT-1 oncogene|mammary transforming gene 1, mouse, homolog of|phosphoprotein enriched in diabetes
Swissprots	O00511 B1AKZ3 Q15121
Accessions	AAD56775 EAW52733 EAW52734 EAW52735 Q15121 AA837443 AI948916 AK095879 BAG53155 AK311762 BAG34705 BC002426 AAH02426 BC010469 AAH10469 BC022554 AAH22554 BT007252 AAP35916 CR541733 CAG46533 DA131259 DA157938 DA532423 DA538845 DA707281 DQ891821 ABM82747 DQ891824 ABM82750 DQ895008 ABM85934 HY182028 L37385 AAA98120 X86809 CAA60499 Y13736 CAA74076 XM_006711599 XP_006711662 NM_001297576 NP_001284505 NM_001297577 NP_001284506 NM_001297578 NP_001284507 NM_003768 NP_003759 NR_123724
Function	Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface. {ECO:0000250, ECO:0000269|PubMed:10442631, ECO:0000269|PubMed:9670003}.
Subcellular Location	Cytoplasm. Note=Associated with microtubules.
Tissue Specificity	Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose- producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls. {ECO:0000269|PubMed:9670003}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-PEA15-cDNA-Clone - DC00944 from Abgent, a WuXi AppTec company Prices $175.50 Sizes 10 µg Species Human Accession BC002426

PEA15 - MBS1270887 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC010469

PEA15 - MBS1271965 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC022554

PEA15 - MBS1266594 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC002426

Human PEA15 Gene cDNA clone plasmid - HG11276-M from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, C-His tag - HG11276-CH from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11276-ANG from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11276-CY from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid - HG11276-UT from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11276-ACR from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11276-ANR from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, N-His tag - HG11276-NH from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11276-ACG from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11276-NF from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11276-NM from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11276-CF from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11276-CM from Sino Biological Species Human

Human PEA15 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11276-NY from Sino Biological Species Human

Human PEA15 ORF clone(NM_003768.3) - CDCL185691 from Creative biogene Species Human

Human PEA15 ORF Clone (BC002426) - CDCS411449 from Creative biogene Species Human Accession Q15121

Human PEA15 ORF Clone (BC022554) - CDCS411450 from Creative biogene Species Human Accession Q15121

Human PEA15 ORF Clone (BC010469) - CDCS411451 from Creative biogene Species Human Accession Q15121

Human MNAT1 Gene ORF cDNA clone expression plasmid - HG10927-UT from Sino Biological Species Human

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