PEA15

Gene Symbol	PEA15
Entrez Gene	8682
Alt Symbol	HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED
Species	Human
Gene Type	protein-coding
Description	phosphoprotein enriched in astrocytes 15
Other Description	15 kDa phosphoprotein enriched in astrocytes|astrocytic phosphoprotein PEA-15|homolog of mouse MAT-1 oncogene|mammary transforming gene 1, mouse, homolog of|phosphoprotein enriched in diabetes
Swissprots	O00511 B1AKZ3 Q15121
Accessions	AAD56775 EAW52733 EAW52734 EAW52735 Q15121 AA837443 AI948916 AK095879 BAG53155 AK311762 BAG34705 BC002426 AAH02426 BC010469 AAH10469 BC022554 AAH22554 BT007252 AAP35916 CR541733 CAG46533 DA131259 DA157938 DA532423 DA538845 DA707281 DQ891821 ABM82747 DQ891824 ABM82750 DQ895008 ABM85934 HY182028 L37385 AAA98120 X86809 CAA60499 Y13736 CAA74076 XM_006711599 XP_006711662 NM_001297576 NP_001284505 NM_001297577 NP_001284506 NM_001297578 NP_001284507 NM_003768 NP_003759 NR_123724
Function	Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface. {ECO:0000250, ECO:0000269|PubMed:10442631, ECO:0000269|PubMed:9670003}.
Subcellular Location	Cytoplasm. Note=Associated with microtubules.
Tissue Specificity	Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose- producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls. {ECO:0000269|PubMed:9670003}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® PEA-15 siRNA II - 7865 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

SignalSilence ® PEA-15 siRNA I - 7830 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

PEA-15 CRISPR/Cas9 KO Plasmid (h) - sc-416336 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PEA-15 HDR Plasmid (h) - sc-416336-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEA-15 Double Nickase Plasmid (h) - sc-416336-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEA-15 Double Nickase Plasmid (h2) - sc-416336-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEA-15 CRISPR Activation Plasmid (h) - sc-416336-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PEA-15 CRISPR Activation Plasmid (h2) - sc-416336-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PEA-15 Lentiviral Activation Particles (h) - sc-416336-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEA-15 Lentiviral Activation Particles (h2) - sc-416336-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEA-15 siRNA (h) - sc-37485 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PEA-15 shRNA Plasmid (h) - sc-37485-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PEA-15 shRNA (h) Lentiviral Particles - sc-37485-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PEA-15 RNAi - H00008682-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU083041 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16602 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16602 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10634 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10634

PEA15 siRNA (Human) - CRH5713 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PEA15 (NM_003768.3) - SHH373308 from Creative biogene Category siRNA Species Reactivities Human

Human PEA15 siRNA - orb266215 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PEA15 shRNA Plasmid (Human) - CHH5713 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PEA15 miRNA 3'UTR clone - MiUTR3H-05968 from Creative biogene Species Reactivities Human

Search more