STX17

Gene Symbol	STX17
Entrez Gene	55014
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	syntaxin 17
Other Description	syntaxin-17
Swissprots	Q4VXC2 P56962
Accessions	EAW58920 P56962 AI375996 AK000658 BAA91311 AK095262 BAG53017 AK124662 AK295949 BAG58731 AK311412 AL833620 AL834371 CAD39034 BC051790 BC070269 AAH70269 BC101564 AAI01565 BC101566 AAI01567 BC111009 AAI11010 BC143430 DC318495 XM_011518820 XP_011517122 XM_011518821 XP_011517123 XM_011518822 XP_011517124 XM_011518823 XP_011517125 XR_929815 NM_017919 NP_060389
Function	SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355). {ECO:0000269|PubMed:21545355, ECO:0000269|PubMed:23217709}.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein. Smooth endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII- coated vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Note=Has an hairpin-like insertion into membranes. Localized into endoplasmic reticulum membranes, it also localizes to the completed autophagosome membrane upon cell starvation. May also localize to the mitochondria according to PubMed:23217709. A significant amount is also present in the cytosol.
Top Pathways	SNARE interactions in vesicular transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Syntaxin 17 (C-12) - sc-107093 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Syntaxin 17 (I-14) - sc-107095 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-STX17 antibody - ab116113 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-STX17 / Syntaxin 17 Antibody (aa1-30) - LS-C161586 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-STX17 / Syntaxin 17 Antibody (aa1-30, AP) - LS-C270613 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STX17 / Syntaxin 17 Antibody (aa1-30, Biotin) - LS-C270614 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STX17 / Syntaxin 17 Antibody (aa1-30, FITC) - LS-C270615 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STX17 / Syntaxin 17 Antibody (aa1-30, APC) - LS-C270616 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STX17 / Syntaxin 17 Antibody (aa1-30, Azide-free, HRP) - LS-C270617 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STX17 / Syntaxin 17 Antibody (aa1-30, PE) - LS-C270618 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-STX17 / Syntaxin 17 Antibody (aa1-30) - LS-C325475 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

STX17 Antibody - NBP1-93968 from Novus Biologicals Prices $129.00, $419.00 Sizes 25 µl, 100 µl Host Rabbit Clonality Polyclonal

Anti-STX17 antibody produced in rabbit - HPA001204 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ANTI-STX17 (N-TERM) antibody produced in rabbit - SAB1304559 from Sigma-Aldrich Prices $326.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

STX17-Antibody-N-term - AP13599a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

STX17 Antibody - N-terminal region (OAAB09900) - OAAB09900 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

STX17 antibody - 70R-20622 from Fitzgerald Prices $375.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

STX17 Antibody - abx027493 from Abbexa Host Rabbit Clonality Polyclonal

Syntaxin 17 / STX17 antibody - 17815-1-AP from Acris Antibodies Prices $270.00 Sizes 150 µl Host Rabbit Clonality Polyclonal

Rabbit Anti-Human STX17 (N-term) - 102-12073 from RayBiotech Host Rabbit

STX17 antibody (N-term) - STJ43270 from St John's Laboratory Ltd Host Rabbit Clonality Polyclonal Clone RB32919

Syntaxin 17 antibody - 17815-1-AP from Proteintech Group Prices $279.00 Sizes con: 29 μg/150μl Host Rabbit Clonality Polyclonal

STX17, Polyclonal Antibody - MBS6007863 from MyBioSource Prices $550.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

syntaxin 17 , Polyclonal Antibody - MBS713140 from MyBioSource Prices $230.00, $500.00 Sizes 50 µl, 150 µl Host Rabbit Clonality Polyclonal

Anti-Syntaxin 17 Antibody - ABC970 from EMD Millipore Prices $299.00 Sizes 100 μg Host Rabbit Clonality Polyclonal

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