STX17

Gene Symbol	STX17
Entrez Gene	55014
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	syntaxin 17
Other Description	syntaxin-17
Swissprots	Q4VXC2 P56962
Accessions	EAW58920 P56962 AI375996 AK000658 BAA91311 AK095262 BAG53017 AK124662 AK295949 BAG58731 AK311412 AL833620 AL834371 CAD39034 BC051790 BC070269 AAH70269 BC101564 AAI01565 BC101566 AAI01567 BC111009 AAI11010 BC143430 DC318495 XM_011518820 XP_011517122 XM_011518821 XP_011517123 XM_011518822 XP_011517124 XM_011518823 XP_011517125 XR_929815 NM_017919 NP_060389
Function	SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (PubMed:21545355). {ECO:0000269|PubMed:21545355, ECO:0000269|PubMed:23217709}.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein. Smooth endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII- coated vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Note=Has an hairpin-like insertion into membranes. Localized into endoplasmic reticulum membranes, it also localizes to the completed autophagosome membrane upon cell starvation. May also localize to the mitochondria according to PubMed:23217709. A significant amount is also present in the cytosol.
Top Pathways	SNARE interactions in vesicular transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human STX17 protein fragment - ab171699 from Abcam Category Protein Source E. coli Species Human

STX17 / Syntaxin 17 Antibody Blocking Peptide - LS-E2557 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human STX17 Protein - NBP2-22842 from Novus Biologicals Category Protein Prices $299.00 Sizes 50 µg Source E.coli Species Human

STX17-Antibody-N-term-Blocking-peptide - BP13599a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

STX17 protein (His tag) - 80R-3050 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

Syntaxin 17 / STX17 (1-229, His-tag) - AR51168PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

Syntaxin 17 / STX17 (1-229, His-tag) - AR51168PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

STX17, 1-229aa, Human, His tag, E.coli - 01-P2344 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

STX17 fusion protein - Ag12134 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

STX17 fusion protein - Ag12378 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human STX17, His-tagged - STX17-2344H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human STX17, GST-tagged - STX17-3025H from Creative Biomart Category Protein Source E.coli Species Human

STX17, 1-229aa, Human, His tag, E.coli - ATGP2344 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

Syntaxin-17 Protein (Recombinant) - abx262704 from Abbexa Category Protein

Human STX17 protein - orb260122 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 2 μg, 10 μg Species Human

STX17 Recombinant Protein Antigen - NBP1-93968PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

STX17 Peptide, Human - M34GP15356H from Creative Peptides Category Peptide Source Synthetic. Species Human

STX17 - PAT-82343-1 from Nordic BioSite Category Protein Species Human

STX17 - PAT-82343-2 from Nordic BioSite Category Protein Species Human

Syntaxin-17, Human Recombinant - 228-21820-1 from RayBiotech Category Protein Species Human

STX17, Recombinant Protein - MBS204891 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 50 µg, 250 µg Source E Coli Species Human

Syntaxin-17, Recombinant Protein - MBS145468 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

Syntaxin-17 (STX17), Recombinant Protein - MBS7030610 from MyBioSource Category Protein Prices $1,115.00, $2,100.00, $3,310.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Species Human

Syntaxin-17 (STX17), Recombinant Protein - MBS968280 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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