TNK1

Gene Symbol	TNK1
Entrez Gene	8711
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	tyrosine kinase, non-receptor, 1
Other Description	CD38 negative kinase 1|non-receptor tyrosine-protein kinase TNK1
Swissprots	O95364 Q8IYI4 Q13470
Accessions	AAC99412 CCQ43245 EAW90203 EAW90204 Q13470 AI810287 AK225403 AK310684 AK311063 BC035782 AAH35782 DA089305 DB287365 DQ891230 ABM82156 DQ894414 ABM85340 U43408 AAC50427 XM_011524045 XP_011522347 XM_011524046 XP_011522348 XM_011524047 XP_011522349 XM_011524048 XP_011522350 NM_001251902 NP_001238831 NM_003985 NP_003976
Function	Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction. {ECO:0000269|PubMed:10873601, ECO:0000269|PubMed:18974114}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:10873601}. Membrane {ECO:0000269|PubMed:10873601}; Peripheral membrane protein {ECO:0000269|PubMed:10873601}.
Tissue Specificity	Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain. {ECO:0000269|PubMed:10873601, ECO:0000269|PubMed:8632913}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tnk1 protein fragment - ab160156 from Abcam Category Protein Source Wheat germ Species Human

TNK1 Antibody Blocking Peptide - LS-E9223 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNK1 Antibody Blocking Peptide - LS-E23726 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Tnk1 Protein - H00008711-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Tnk1 Peptide - P2766 from Novus Biologicals Category Peptide Species Human

TNK1-Antibody-Center-Blocking-Peptide - BP7722c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNK1 - H00008711-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TNK1 - H00008711-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TNK1 fusion protein - Ag5402 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human TNK1, His-tagged - TNK1-3326H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Tyrosine Kinase, Non-receptor, 1, GST-tagged - TNK1-701H from Creative Biomart Category Protein Source Baculovirus.

Recombinant Human Non-receptor tyrosine-protein kinase TNK1(TNK1) - CSB-YP622659HU CSB-EP622659HU CSB-BP622659HU CSB-MP622659HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Tnk1 Recombinant Protein Antigen - NBP1-86477PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TNK1-Blocking-Peptide-C-term - BP21591b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNK1-Blocking-Peptide-Center-I332 - BP7722d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNK1-Blocking-Peptide-N-term - BP7722a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNK1 Peptide, Human - M34GP16387H from Creative Peptides Category Peptide Source Synthetic. Species Human

Non-receptor tyrosine-protein kinase TNK1 (TNK1), Recombinant Protein - MBS1484325 from MyBioSource Category Protein Prices $1,470.00, $1,470.00, $1,695.00, $1,695.00, $2,500.00, $2,500.00, $2,940.00, $2,940.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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