TNK1

Gene Symbol TNK1
Entrez Gene 8711
Alt Symbol -
Species Human
Gene Type protein-coding
Description tyrosine kinase, non-receptor, 1
Other Description CD38 negative kinase 1|non-receptor tyrosine-protein kinase TNK1
Swissprots O95364 Q8IYI4 Q13470
Accessions AAC99412 CCQ43245 EAW90203 EAW90204 Q13470 AI810287 AK225403 AK310684 AK311063 BC035782 AAH35782 DA089305 DB287365 DQ891230 ABM82156 DQ894414 ABM85340 U43408 AAC50427 XM_011524045 XP_011522347 XM_011524046 XP_011522348 XM_011524047 XP_011522349 XM_011524048 XP_011522350 NM_001251902 NP_001238831 NM_003985 NP_003976
Function Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction. {ECO:0000269|PubMed:10873601, ECO:0000269|PubMed:18974114}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10873601}. Membrane {ECO:0000269|PubMed:10873601}; Peripheral membrane protein {ECO:0000269|PubMed:10873601}.
Tissue Specificity Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain. {ECO:0000269|PubMed:10873601, ECO:0000269|PubMed:8632913}.

TNK1 CRISPR/Cas9 KO Plasmid (h) - sc-406539 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 HDR Plasmid (h) - sc-406539-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 Double Nickase Plasmid (h) - sc-406539-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 Double Nickase Plasmid (h2) - sc-406539-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 CRISPR Activation Plasmid (h) - sc-406539-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 CRISPR Activation Plasmid (h2) - sc-406539-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 Lentiviral Activation Particles (h) - sc-406539-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 Lentiviral Activation Particles (h2) - sc-406539-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 siRNA (h) - sc-93553 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TNK1 shRNA Plasmid (h) - sc-93553-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TNK1 shRNA (h) Lentiviral Particles - sc-93553-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Tnk1 RNAi - H00008711-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU082751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK2305 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2303 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2304 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN21775 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21775 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06039 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06039

TNK1 siRNA (Human) - CRH5734 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNK1 - MBS8205706 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNK1 CRISPR/Cas9 KO Plasmid (h2) - sc-406539-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNK1 HDR Plasmid (h2) - sc-406539-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human TNK1 (NM_003985.4) - SHH432260 from Creative biogene

Category siRNA
Species Reactivities Human

Human TNK1 siRNA - orb266236 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
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