Gene Symbol | CYP2A13 |
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Entrez Gene | 1553 |
Alt Symbol | CPAD, CYP2A, CYPIIA13 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 2, subfamily A, polypeptide 13 |
Other Description | cytochrome P450 2A13|cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13 |
Swissprots | Q6R569 Q16696 Q9H2X2 Q6R570 Q53YR8 |
Accessions | AAB40519 EAW57016 Q16696 AF209774 AAG35775 AY513604 AAR90935 AY513605 AAR90936 AY513606 AAR90937 AY513607 AAR90938 AY513608 AAR90939 AY513609 AAR90940 BC148422 AAI48423 BC153000 AAI53001 BM975825 NM_000766 NP_000757 |
Function | Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N- dimethylaniline, 2'-methoxyacetophenone, N- nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity. {ECO:0000269|PubMed:18779312}. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
Tissue Specificity | Expressed in liver and a number of extrahepatic tissues, including nasal mucosa, lung, trachea, brain, mammary gland, prostate, testis, and uterus, but not in heart, kidney, bone marrow, colon, small intestine, spleen, stomach, thymus, or skeletal muscle. {ECO:0000269|PubMed:11016631}. |
Top Pathways | Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450 |
Anti-CYP2A13 antibody - ab65127 from Abcam
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Anti-CYP2A13 antibody - ab167594 from Abcam
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Anti-CYP2A13 antibody - C-terminal - ab135703 from Abcam
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Anti-CYP2A13 Antibody - LS-C307840 from LifeSpan Bioscience
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Anti-CYP2A13 Antibody - LS-C310067 from LifeSpan Bioscience
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Anti-CYP2A13 Antibody (aa401-450) - LS-C31969 from LifeSpan Bioscience
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Anti-CYP2A13 Antibody (aa311-360) - LS-C119494 from LifeSpan Bioscience
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Anti-CYP2A13 Antibody (Asn338) - LS-C176855 from LifeSpan Bioscience
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Anti-CYP2A13 Antibody (aa454-484) - LS-C167216 from LifeSpan Bioscience
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CYP2A13 Antibody - NB100-92424 from Novus Biologicals
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CYP2A13 Antibody - NBP2-33467 from Novus Biologicals
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CYP2A13 Antibody - NBP1-62400 from Novus Biologicals
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CYP2A13 Antibody - H00001553-D01P from Novus Biologicals
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CYP2A13 Antibody - H00001553-B01P from Novus Biologicals
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CYP2A13 Antibody - H00001553-D01 from Novus Biologicals
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Anti-CYTOCHROME P450 2A13 antibody produced in rabbit - SAB4500586 from Sigma-Aldrich
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Anti-CYP2A13 antibody produced in rabbit - AV41803 from Sigma-Aldrich
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Anti-CYP2A13 antibody produced in rabbit - SAB1401105 from Sigma-Aldrich
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Anti-CYP2A13 antibody produced in rabbit - HPA046713 from Sigma-Aldrich
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Anti-CYP2A13 antibody produced in mouse - SAB1405684 from Sigma-Aldrich
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CYP2A13 antibody - C-terminal region (ARP41803_T100) - ARP41803_T100 from Aviva Systems Biology
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CYP2A13-Antibody-C-term - AP8649b from Abgent, a WuXi AppTec company
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CYP2A13 Antibody - C-terminal region (OAAB05243) - OAAB05243 from Aviva Systems Biology
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CYP2A13 antibody [C1C2], Internal - GTX103361 from GeneTex
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CYP2A13 antibody, C-term - GTX81118 from GeneTex
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