Gene Symbol | NSDHL |
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Entrez Gene | 50814 |
Alt Symbol | H105E3, SDR31E1, XAP104 |
Species | Human |
Gene Type | protein-coding |
Description | NAD(P) dependent steroid dehydrogenase-like |
Other Description | protein H105e3|short chain dehydrogenase/reductase family 31E, member 1|sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating |
Swissprots | O00344 D3DWT6 Q15738 |
Accessions | EAW72897 EAW72898 EAW72899 Q15738 AK026549 AM393176 CAL38054 AM393670 CAL38546 BC000245 AAH00245 BC007816 AAH07816 DQ892488 ABM83414 DQ895699 ABM86625 U47105 AAC50558 XM_011531178 XP_011529480 NM_001129765 NP_001123237 NM_015922 NP_057006 |
Function | Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis. {ECO:0000269|PubMed:14506130}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:14506130}; Single-pass membrane protein {ECO:0000269|PubMed:14506130}. Lipid droplet {ECO:0000269|PubMed:14506130}. Note=Trafficking through the Golgi is necessary for ER membrane localization. |
Tissue Specificity | Brain, heart, liver, lung, kidney, skin and placenta. |
Top Pathways | Steroid biosynthesis |
Human NSDHL full length protein - ab162360 from Abcam
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Human NSDHL protein fragment - ab162361 from Abcam
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Human NSDHL protein fragment - ab174410 from Abcam
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NSDHL Antibody Blocking Peptide - LS-E17114 from LifeSpan Bioscience
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NSDHL Partial Recombinant Protein - H00050814-Q01 from Novus Biologicals
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NSDHL Recombinant Protein - H00050814-P01 from Novus Biologicals
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NSDHL Protein - NBP2-23258 from Novus Biologicals
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NSDHL Blocking Peptide - 33R-7828 from Fitzgerald
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NSDHL protein (His tag) - 80R-3593 from Fitzgerald
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NSDHL (1-297, His-tag) - AR51280PU-N from Acris Antibodies
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NSDHL (1-297, His-tag) - AR51280PU-S from Acris Antibodies
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NSDHL - H00050814-P01-10 from Acris Antibodies
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NSDHL - H00050814-P01-25 from Acris Antibodies
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NSDHL - H00050814-Q01-10 from Acris Antibodies
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NSDHL - H00050814-Q01-25 from Acris Antibodies
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NSDHL, 1-297aa, Human, His tag, E.coli - 01-P2460 from ARP American Research Products
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NSDHL fusion protein - Ag7097 from Proteintech Group
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NSDHL fusion protein - Ag7230 from Proteintech Group
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Recombinant human NSDHL, His-tagged - NSDHL-2460H from Creative Biomart
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Recombinant Human NSDHL, GST-tagged - NSDHL-1371H from Creative Biomart
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NSDHL, 1-297aa, Human, His tag, E.coli - ATGP2460 from ATGen
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NSDHL Recombinant Protein Antigen - NBP1-83307PEP from Novus Biologicals
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NSDHL Recombinant Protein Antigen - NBP1-83306PEP from Novus Biologicals
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Human NSDHL protein - orb259988 from Biorbyt
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NSDHL Peptide, Human - M34GP10642H from Creative Peptides
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