NSDHL

Gene Symbol NSDHL
Entrez Gene 50814
Alt Symbol H105E3, SDR31E1, XAP104
Species Human
Gene Type protein-coding
Description NAD(P) dependent steroid dehydrogenase-like
Other Description protein H105e3|short chain dehydrogenase/reductase family 31E, member 1|sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
Swissprots O00344 D3DWT6 Q15738
Accessions EAW72897 EAW72898 EAW72899 Q15738 AK026549 AM393176 CAL38054 AM393670 CAL38546 BC000245 AAH00245 BC007816 AAH07816 DQ892488 ABM83414 DQ895699 ABM86625 U47105 AAC50558 XM_011531178 XP_011529480 NM_001129765 NP_001123237 NM_015922 NP_057006
Function Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis. {ECO:0000269|PubMed:14506130}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:14506130}; Single-pass membrane protein {ECO:0000269|PubMed:14506130}. Lipid droplet {ECO:0000269|PubMed:14506130}. Note=Trafficking through the Golgi is necessary for ER membrane localization.
Tissue Specificity Brain, heart, liver, lung, kidney, skin and placenta.
Top Pathways Steroid biosynthesis

NSDHL (D-11) - sc-390871 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NSDHL (D-11): sc-390871. Western blot analysis of NSDHL expression in non-transfected 293T: sc-117752 (A), mouse NSDHL transfected 293T: sc-122135 (B), F9 (C), A-431 (D) and HeLa (E) whole cell lysates.

NSDHL (B-5) - sc-390994 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NSDHL (B-5): sc-390994. Western blot analysis of NSDHL expression in A-431 (A), F9 (B) and HeLa (C) whole cell lysates.

NSDHL (H-195) - sc-366841 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NSDHL (H-195): sc-366841. Western blot analysis of NSDHL expression in non-transfected: sc-117752 (A) and mouse NSDHL transfected: sc-122135 (B) 293T whole cell lysates.

NSDHL (M-13) - sc-161966 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NSDHL (M-13): sc-161966. Western blot analysis of NSDHL expression in NIH/3T3 (A), KNRK (B), HeLa (C) and F9 (D) whole cell lysates and mouse liver tissue extract (E).

NSDHL (T-17) - sc-161969 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NSDHL (T-17): sc-161969. Western blot analysis of NSDHL expression in F9 (A) and A-431 (B) whole cell lysates.

Anti-NSDHL antibody - ab102805 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-NSDHL antibody (ab102805) at 5 µg/ml + Mouse lung tissue lysate at 50 µgSecondaryGoat anti-Mouse IgG HRP at 1/2500 dilution

Anti-NSDHL antibody - ab92904 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-NSDHL antibody (ab92904) at 1/500 dilution + Human liver tissue lysate at 50 µg

Anti-NSDHL antibody - ab197332 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NSDHL antibody (ab197332) at 1/500 dilutionLane 1 : A431 cell lysateLane 2 : HeLa cell lysateLane 3 : HepG2 cell lysate

Anti-NSDHL antibody - ab54755 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab54755 NSDHL antibody at 1ug/ml.

Anti-NSDHL antibody [EPR14489(2)] - ab199730 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14489(2)
All lanes : Anti-NSDHL antibody [EPR14489(2)] (ab199730) at 1/1000 dilutionLane 1 : A431 (Human epidermoid carcinoma) whole cell lysateLane 2 : HeLa (Human epithelial cells from cervix adenocarcinoma) whole cell lysateLane 3 : HepG2 (Human liver hepatocellular carcinoma) whole cell lysateLane 4 : Human fetal brain lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated) at 1/1000 dilution

Anti-NSDHL antibody [EPR14490] - ab190353 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14490
All lanes : Anti-NSDHL antibody [EPR14490] (ab190353) at 1/10000 dilutionLane 1 : A431 cell lysateLane 2 : HeLa cell lysateLane 3 : Human fetal brain lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-NSDHL Antibody (aa181-230) - LS-C80999 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.

NSDHL Antibody - NBP1-83306 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NSDHL Antibody [NBP1-83306] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18 Lane 2: Human cell line RT-4 Lane 3: Human cell line U-251MG sp Lane 4: Human cell line A-431 Lane 5: Human liver tissue

NSDHL Antibody - NBP1-83307 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NSDHL Antibody [NBP1-83307] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18 Lane 2: Human cell line RT-4 Lane 3: Human cell line U-251MG sp Lane 4: Human cell line A-431 Lane 5: Human liver tissue

NSDHL Antibody - NBP1-59799 from Novus Biologicals

Prices $139.00, $299.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

NSDHL Antibody - H00050814-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: NSDHL Antibody [H00050814-D01P] - Analysis of NSDHL expression in mouse lung.

NSDHL Antibody (6E3) - H00050814-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E3
Western Blot: NSDHL Antibody (6E3) [H00050814-M01] - NSDHL monoclonal antibody (M01), clone 6E3. Analysis of NSDHL expression in Raw 264.7.

NSDHL Antibody - NBP2-19590 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NSDHL Antibody [NBP2-19590] - Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE gel, diluted at 1:1000.

NSDHL Antibody - H00050814-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NSDHL Antibody - H00050814-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Monoclonal Anti-NSDHL antibody produced in mouse - WH0050814M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E3
<B>Immunoblotting</B><BR/>Monoclonal Anti-NSDHL, <B>Cat. No. WH0050814M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~38.21 kDa using immunogen protein lysate.

Anti-NSDHL antibody produced in rabbit - AV47199 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV47199</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 2.5 μg/mL in cell type HepG2

Anti-NSDHL antibody produced in rabbit - SAB1410882 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NSDHL: <B>Cat. No. SAB1410882</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~41.9 kDa using A-431 lysate.

Anti-NSDHL antibody produced in rabbit - HPA000571 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NSDHL: <B>Cat. No. HPA000571</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue showing cytoplasmic and/or membranous staining of hepatocytes.

Anti-NSDHL antibody produced in rabbit - HPA000248 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NSDHL: <B>Cat. No. HPA000248</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue showing cytoplasmic and/or membranous staining of hepatocytes.
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