SIPA1

Gene Symbol SIPA1
Entrez Gene 6494
Alt Symbol SPA1
Species Human
Gene Type protein-coding
Description signal-induced proliferation-associated 1
Other Description GTPase-activating protein Spa-1|p130 SPA-1|signal-induced proliferation-associated gene 1|signal-induced proliferation-associated protein 1|sipa-1
Swissprots O60618 Q96FS4 O60484 O14518 Q2YD83
Accessions AAC32559 EAW74421 EAW74422 EAW74423 Q96FS4 AB005666 BAA22197 AF029789 AAC32547 AI307277 AK303551 BAG64575 AK308234 AK310068 BC010492 AAH10492 BC110353 AAI10354 BM677738 DN999403 XM_005274189 XP_005274246 XM_011545214 XP_011543516 XM_011545215 XP_011543517 XR_247210 XR_950017 NM_006747 NP_006738 NM_153253 NP_694985
Function GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state. {ECO:0000269|PubMed:9346962}.
Subcellular Location Nucleus. Cytoplasm, perinuclear region. Endomembrane system; Peripheral membrane protein. Note=Mostly localized in the perinuclear membraneous region.
Tissue Specificity Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
Top Pathways Leukocyte transendothelial migration, Rap1 signaling pathway

Human SIPA1 peptide - ab23193 from Abcam

Category Peptide
Species Human

Human SIPA1 protein fragment - ab159512 from Abcam

Category Protein
Source Wheat germ
Species Human
ab159512 on a 12.5% SDS-PAGE stained with Coomassie Blue.

SIPA1 Antibody Blocking Peptide - LS-E4628 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SIPA1 Antibody Blocking Peptide - LS-E25674 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SIPA1 Antibody Blocking Peptide - LS-E21512 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SIPA1 Antibody Blocking Peptide - LS-E31216 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Recombinant Human SIPA1 Protein - H00006494-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SIPA1-Antibody-C-term-Blocking-Peptide - BP16989b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SIPA1 blocking peptide - GTX10162-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

SIPA1 Blocking Peptide - 33R-8976 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SIPA1 Peptide - AC21-0504-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

SIPA1 / SPA1 - H00006494-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SIPA1 / SPA1 - H00006494-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SIPA1 / SPA1 (N-term) Control Peptide - AP55608CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

SIPA1 Peptide - 46-371P from ProSci

Category Peptide
Species Human

SIPA1 Peptide - 6643P from ProSci

Category Peptide
Species Human

SIPA1 fusion protein - ag17874 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

SIPA1 fusion protein - ag3383 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Signal-induced proliferation-associated protein 1(SIPA1) ,part - CSB-YP822213HU CSB-EP822213HU CSB-BP822213HU CSB-MP822213HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

SPA1/SIPA1, Peptide - MBS425748 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human

SIPA1 Protein - NBP2-32620PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

SIPA1 fusion protein - Ag25383 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

SIPA1 Peptide, Human - M34GP14258H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Signal-induced proliferation-associated protein 1 (SIPA1), partial, Recombinant Protein - MBS1485144 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
Search more