TNRC6A

Gene Symbol	TNRC6A
Entrez Gene	27327
Alt Symbol	CAGH26, GW1, GW182, TNRC6
Species	Human
Gene Type	protein-coding
Description	trinucleotide repeat containing 6A
Other Description	CAG repeat protein 26|EDIE|EMSY interactor protein|GW182 autoantigen|glycine-tryptophan protein of 182 kDa|trinucleotide repeat-containing gene 6A protein
Swissprots	Q9NV59 Q8NDV7 Q9P268 Q658L5 O15408 Q8TCR0 Q8TBT8 Q6NVB5 C9JAR8 Q8NEZ0
Accessions	EAW55782 EAW55783 EAW55784 EAW55785 EAW55786 EAW55787 Q8NDV7 AB040893 BAA95984 AJ492221 CAD37348 AK001773 BAA91899 AK025277 AK025696 AK094542 BAG52884 AK299905 BAG61746 AL713750 CAD28525 AL833757 CAH56236 AY035864 AAK62026 BC024324 AAH24324 BC068209 BC172409 AAI72409 BE158958 BU743266 U23860 U80739 AAB91438 XM_005255254 XP_005255311 XM_005255257 XP_005255314 XM_006721039 XP_006721102 XM_011545791 XP_011544093 XM_011545792 XP_011544094 XM_011545793 XP_011544095 XM_011545794 XP_011544096 XM_011545795 XP_011544097 XM_011545796 XP_011544098 NM_014494 NP_055309
Function	Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes. {ECO:0000269|PubMed:16284622, ECO:0000269|PubMed:16284623, ECO:0000269|PubMed:17596515, ECO:0000269|PubMed:17671087, ECO:0000269|PubMed:19056672, ECO:0000269|PubMed:19304925}.
Subcellular Location	Cytoplasm, P-body {ECO:0000269|PubMed:11950943, ECO:0000269|PubMed:13130130, ECO:0000269|PubMed:15494374, ECO:0000269|PubMed:15908945, ECO:0000269|PubMed:16284622, ECO:0000269|PubMed:16284623, ECO:0000269|PubMed:16906129, ECO:0000269|PubMed:18946079, ECO:0000269|PubMed:19056672, ECO:0000269|PubMed:19324964}. Note=Mammalian P-bodies are also known as GW bodies (GWBs).
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:11950943}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TNRC6A - MBS1266689 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC068209

Human TNRC6A Gene ORF cDNA clone expression plasmid - HG15343-UT from Sino Biological Species Human

Human TNRC6A partial Gene cDNA Clone, expression ready, HA-tagged - HG15343-G-Y from Sino Biological Species Human Accession BC068209

Human TNRC6A Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15343-ANG from Sino Biological Species Human

Human TNRC6A partial Gene cDNA Clone, expression ready, C-GFPSpark-tagged - HG15343-ACG from Sino Biological Species Human Accession BC068209

Human TNRC6A Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15343-NF from Sino Biological Species Human

Human TNRC6A Gene ORF cDNA clone expression plasmid, N-HA tag - HG15343-NY from Sino Biological Species Human

Human TNRC6A Gene ORF cDNA clone expression plasmid, N-His tag - HG15343-NH from Sino Biological Species Human

Human TNRC6A Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15343-CF from Sino Biological Species Human

Human TNRC6A Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15343-NM from Sino Biological Species Human

Human TNRC6A Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15343-CM from Sino Biological Species Human

Human TNRC6A Gene ORF cDNA clone expression plasmid, C-His tag - HG15343-CH from Sino Biological Species Human

Human TNRC6A Gene ORF cDNA clone expression plasmid, C-HA tag - HG15343-CY from Sino Biological Species Human

human TNRC6A ORF clone (NM_014494.2) - CDCH093832 from Creative biogene Species Human

Human TNRC6A ORF Clone (BC068209) - CDCS413666 from Creative biogene Species Human Accession Q8NDV7

Human TNRC6A ORF clone (BC068209) - CDCB158254 from Creative biogene Species Human

Human TNRC6A cDNA Clone(NM_014494.2) - CDFH020083 from Creative biogene Species Human

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