TNRC6A

Gene Symbol	TNRC6A
Entrez Gene	27327
Alt Symbol	CAGH26, GW1, GW182, TNRC6
Species	Human
Gene Type	protein-coding
Description	trinucleotide repeat containing 6A
Other Description	CAG repeat protein 26|EDIE|EMSY interactor protein|GW182 autoantigen|glycine-tryptophan protein of 182 kDa|trinucleotide repeat-containing gene 6A protein
Swissprots	Q9NV59 Q8NDV7 Q9P268 Q658L5 O15408 Q8TCR0 Q8TBT8 Q6NVB5 C9JAR8 Q8NEZ0
Accessions	EAW55782 EAW55783 EAW55784 EAW55785 EAW55786 EAW55787 Q8NDV7 AB040893 BAA95984 AJ492221 CAD37348 AK001773 BAA91899 AK025277 AK025696 AK094542 BAG52884 AK299905 BAG61746 AL713750 CAD28525 AL833757 CAH56236 AY035864 AAK62026 BC024324 AAH24324 BC068209 BC172409 AAI72409 BE158958 BU743266 U23860 U80739 AAB91438 XM_005255254 XP_005255311 XM_005255257 XP_005255314 XM_006721039 XP_006721102 XM_011545791 XP_011544093 XM_011545792 XP_011544094 XM_011545793 XP_011544095 XM_011545794 XP_011544096 XM_011545795 XP_011544097 XM_011545796 XP_011544098 NM_014494 NP_055309
Function	Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes. {ECO:0000269|PubMed:16284622, ECO:0000269|PubMed:16284623, ECO:0000269|PubMed:17596515, ECO:0000269|PubMed:17671087, ECO:0000269|PubMed:19056672, ECO:0000269|PubMed:19304925}.
Subcellular Location	Cytoplasm, P-body {ECO:0000269|PubMed:11950943, ECO:0000269|PubMed:13130130, ECO:0000269|PubMed:15494374, ECO:0000269|PubMed:15908945, ECO:0000269|PubMed:16284622, ECO:0000269|PubMed:16284623, ECO:0000269|PubMed:16906129, ECO:0000269|PubMed:18946079, ECO:0000269|PubMed:19056672, ECO:0000269|PubMed:19324964}. Note=Mammalian P-bodies are also known as GW bodies (GWBs).
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:11950943}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GW182 peptide - ab176455 from Abcam Category Peptide Prices $467.00 Sizes 1 mg

TNRC6A / GW182 Antibody Blocking Peptide - LS-E15022 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GW182 Protein - P3791 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Source Yeast Species Human

TNRC6A Blocking Peptide - 33R-7878 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TNRC6A fusion protein - ag3794 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Trinucleotide repeat-containing gene 6A protein(TNRC6A) ,parti - CSB-YP839859HU CSB-EP839859HU CSB-BP839859HU CSB-MP839859HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TNRC6A Peptide - abx164627 from Abbexa Category Peptide Species Human

Recombinant Trinucleotide Repeat Containing Protein 6A (TNRC6A) - RPC801Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Trinucleotide Repeat Containing Protein 6A (TNRC6A) - RPC801Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Trinucleotide Repeat Containing Protein 6A (TNRC6A) - RPC801Hu01 from Cloud-clone Category Protein Source E.coli Species Human

TNRC6A-Blocking-Peptide-Center - BP21900c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNRC6A Peptide, Human - M34GP16410H from Creative Peptides Category Peptide Source Synthetic. Species Human

TNRC6A Recombinant Protein (OPCD00896) - OPCD00896 from Aviva Systems Biology Category Protein Source E.coli Species Human

Search more