Gene Symbol | GPX7 |
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Entrez Gene | 2882 |
Alt Symbol | CL683, GPX6, GPx-7, GSHPx-7, NPGPx |
Species | Human |
Gene Type | protein-coding |
Description | glutathione peroxidase 7 |
Other Description | glutathione peroxidase 6|non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase |
Swissprots | Q96SL4 O95337 Q5T501 |
Accessions | AAY88741 EAX06777 Q96SL4 AF091092 AAC72961 AF320068 AAN76501 AK027683 BAB55294 AY358402 AAQ88768 BC032788 AAH32788 BI550170 BU627166 DQ894018 ABM84944 NM_015696 NP_056511 |
Function | It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. {ECO:0000269|PubMed:22157330}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids. {ECO:0000269|PubMed:22157330}. |
Top Pathways | Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism |
GPX7-Over-expression-Lysate - LY12592a from Abgent, a WuXi AppTec company
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GPX7 293T Cell Transient Overexpression Lysate(Denatured) - H00002882-T01 from Acris Antibodies
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GPX7 overexpression lysate - LY414390 from Acris Antibodies
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GPX7 293 Cell Lysate - 406924 from ABBIOTEC
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Glutathione Peroxidase 7 Overexpression Lysate (Denatured) - H00002882-T01 from Novus Biologicals
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Glutathione Peroxidase 7 Overexpression Lysate (Native) - NBL1-11318 from Novus Biologicals
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GPX7 Over-expression Lysate Product - GWB-8F1C0D from Genway Biotech
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Human GPX7 / Glutathione Peroxidase 7 HEK293 Cell Lysate (WB positive control) - 12651-H02HL-300 from Sino Biological
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Human GPX7 Human Cells Transfected Lysate (positive control) (denatured) - orb174154 from Biorbyt
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Panoply™ Human GPX7 Knockdown Stable Cell Line - CSC-DC006624 from Creative biogene
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