Gene Symbol | GPX7 |
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Entrez Gene | 2882 |
Alt Symbol | CL683, GPX6, GPx-7, GSHPx-7, NPGPx |
Species | Human |
Gene Type | protein-coding |
Description | glutathione peroxidase 7 |
Other Description | glutathione peroxidase 6|non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase |
Swissprots | Q96SL4 O95337 Q5T501 |
Accessions | AAY88741 EAX06777 Q96SL4 AF091092 AAC72961 AF320068 AAN76501 AK027683 BAB55294 AY358402 AAQ88768 BC032788 AAH32788 BI550170 BU627166 DQ894018 ABM84944 NM_015696 NP_056511 |
Function | It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. {ECO:0000269|PubMed:22157330}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids. {ECO:0000269|PubMed:22157330}. |
Top Pathways | Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism |
Human Glutathione Peroxidase 7 full length protein - ab117062 from Abcam
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Human Glutathione Peroxidase 7 full length protein - ab123185 from Abcam
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Human Glutathione Peroxidase 7 full length protein - ab109355 from Abcam
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GPX6 / GPX-6 Antibody Blocking Peptide - LS-E26130 from LifeSpan Bioscience
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GPX7 Antibody Blocking Peptide - LS-E26131 from LifeSpan Bioscience
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GPX7 Antibody Blocking Peptide - LS-E19984 from LifeSpan Bioscience
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Glutathione Peroxidase 7 Recombinant Protein - H00002882-P01 from Novus Biologicals
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Recombinant Human Glutathione Peroxidase 7 Protein - NBP1-78890 from Novus Biologicals
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GPX7 blocking peptide - GTX89305-PEP from GeneTex
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Human GPX7 protein - orb168431 from Biorbyt
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Human GPX7 protein - orb138951 from Biorbyt
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Goat anti GPX6 antibody Immunizing peptide - orb16851 from Biorbyt
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GPX7 protein (His tag) - 80R-2133 from Fitzgerald
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Glutathione Peroxidase 7 Peptide - AC21-0961-P from Abcore
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Glutathione peroxidase 7 / GPX7 (20-187, His-tag) - AR50216PU-N from Acris Antibodies
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Glutathione peroxidase 7 / GPX7 (20-187, His-tag) - AR50216PU-S from Acris Antibodies
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Glutathione peroxidase 7 / GPX7 - H00002882-P01-10 from Acris Antibodies
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Glutathione peroxidase 7 / GPX7 - H00002882-P01-25 from Acris Antibodies
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Glutathione Peroxidase 7, Human Recombinant - 228-12388-1 from RayBiotech
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Recombinant Human Glutathione Peroxidase 7 - 228-12388-2 from RayBiotech
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Recombinant Human Glutathione Peroxidase 7 - 228-12388-3 from RayBiotech
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GPX7, 20-187aa, Human, His tag, E.coli - 01-P1391 from ARP American Research Products
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GPX7 Peptide - 45-702P from ProSci
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GPX7 fusion protein - Ag4328 from Proteintech Group
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GPX7 Human - ENPS-244 from NeoScientific
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