PTPRN

Gene Symbol PTPRN
Entrez Gene 5798
Alt Symbol IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, N
Other Description ICA 512|PTP IA-2|islet cell antigen 2|islet cell antigen 512|islet cell autoantigen 3|protein tyrosine phosphatase-like N|receptor-type tyrosine-protein phosphatase-like N
Swissprots Q53QD6 Q08319 B4DK12 Q6NSL1 F5GZS3 Q16849
Accessions AAY24038 EAW70724 EAW70725 EAW70726 Q16849 AB209368 BAD92605 AK054765 AK122679 BAG53662 AK291469 BAF84158 AK294490 BAG57712 AK296335 BAG59024 AK314574 BC007713 AAH07713 BC070053 AAH70053 BT006975 AAP35621 DC344431 DC352946 L18983 AAA90974 X62899 CAA44688 XM_011511566 XP_011509868 NM_001199763 NP_001186692 NM_001199764 NP_001186693 NM_002846 NP_002837
Function Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. {ECO:0000269|PubMed:8144912, ECO:0000269|PubMed:8641276}.
Subcellular Location Membrane; Single-pass type I membrane protein. Note=Neuroendocrine secretory granules.
Tissue Specificity Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary. {ECO:0000269|PubMed:8024693}.
Top Pathways Type I diabetes mellitus

PTP IA-2 (98/4H6) - sc-130570 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PTP IA-2 (98/4H6): sc-130570. Western blot analysis of PTP IA-2 expression in non-transfected: sc-117752 (A) and human PTP IA-2 transfected: sc-158898 (B) 293T whole cell lysates.

PTP IA-2 (A-5) - sc-390101 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PTP IA-2 (A-5): sc-390101. Western blot analysis of PTP IA-2 expression in AtT-20/D16vF2 (A), SK-N-MC (B), MIA PaCa-2 (C) and IMR-32 (D) whole cell lysates.

PTP IA-2 (G-18) - sc-54750 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PTP IA-2 (H-41) - sc-292265 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PTP IA-2 (H-41): sc-292265. Western blot analysis of PTP IA-2 expression in IMR-32 (A) and MIA PaCa-2 (B) whole cell lysates.

PTP IA-2 (N-17) - sc-54678 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PTP IA-2 (N-17): sc-54678. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islets of Langerhans.

PTP IA-2 (P-15) - sc-54751 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PTP IA-2 (Q-20) - sc-54749 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PTP IA-2 (Q-20): sc54749. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islets of Langerhans.

PTP IA-2 (AFT38) - sc-135672 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
PTP IA-2 (AFT38): sc-135672. Western blot analysis of PTP IA-2 expression in non-transfected (A), Tau transfected (B), PTP IA-2 transfected (C) and GFP-Ub+1 transfected (D) Bosc23 whole cell lysates.

Anti-PTPIA2 / PTPRN antibody - ab198279 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling PTPIA2 / PTPRN with ab198279 at 1/30 dilution.

Anti-PTPIA2 / PTPRN antibody - ab37523 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PTPIA2 / PTPRN antibody (ab37523) at 1/100 dilution + C6 cell lysate

Anti-PTPIA2 / PTPRN antibody [AFT38] - ab75525 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AFT38

Anti-PTPRN / IA-2 Antibody (aa287-316, AP) - LS-C284885 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa287-316, APC) - LS-C284886 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa287-316, Biotin) - LS-C284887 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa287-316, FITC) - LS-C284889 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa287-316, Azide-free, HRP) - LS-C284890 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa287-316, PE) - LS-C284891 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa368-575, Biotin) - LS-C300744 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa368-575, FITC) - LS-C302263 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa32-81) - LS-C80717 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 0.0625 ug/ml. Gel concentration: 12%.

Anti-PTPRN / IA-2 Antibody - LS-C62171 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-PTPRN / IA-2 Antibody (aa287-316) - LS-C324421 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTPRN / IA-2 Antibody (aa287-316) - LS-C162315 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PTPRN Antibody western blot of Jurkat cell line lysates (35 ug/lane). The PTPRN antibody detected the PTPRN protein (arrow).

Anti-PTPRN / IA-2 Antibody (aa368-575) - LS-C296135 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PTPRN / IA-2.

Anti-PTPRN / IA-2 Antibody (clone 8E3) IHC-plus™ - LS-B6395 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 8E3
Anti-PTPRN antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6395 concentration 5 ug/ml.
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