PTPRN

Gene Symbol PTPRN
Entrez Gene 5798
Alt Symbol IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, N
Other Description ICA 512|PTP IA-2|islet cell antigen 2|islet cell antigen 512|islet cell autoantigen 3|protein tyrosine phosphatase-like N|receptor-type tyrosine-protein phosphatase-like N
Swissprots Q53QD6 Q08319 B4DK12 Q6NSL1 F5GZS3 Q16849
Accessions AAY24038 EAW70724 EAW70725 EAW70726 Q16849 AB209368 BAD92605 AK054765 AK122679 BAG53662 AK291469 BAF84158 AK294490 BAG57712 AK296335 BAG59024 AK314574 BC007713 AAH07713 BC070053 AAH70053 BT006975 AAP35621 DC344431 DC352946 L18983 AAA90974 X62899 CAA44688 XM_011511566 XP_011509868 NM_001199763 NP_001186692 NM_001199764 NP_001186693 NM_002846 NP_002837
Function Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. {ECO:0000269|PubMed:8144912, ECO:0000269|PubMed:8641276}.
Subcellular Location Membrane; Single-pass type I membrane protein. Note=Neuroendocrine secretory granules.
Tissue Specificity Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary. {ECO:0000269|PubMed:8024693}.
Top Pathways Type I diabetes mellitus

PTP IA-2 CRISPR/Cas9 KO Plasmid (h) - sc-406833 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTP IA-2 HDR Plasmid (h) - sc-406833-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTP IA-2 Double Nickase Plasmid (h) - sc-406833-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTP IA-2 Double Nickase Plasmid (h2) - sc-406833-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTP IA-2 CRISPR Activation Plasmid (h) - sc-406833-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTP IA-2 CRISPR Activation Plasmid (h2) - sc-406833-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTP IA-2 Lentiviral Activation Particles (h) - sc-406833-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTP IA-2 Lentiviral Activation Particles (h2) - sc-406833-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTP IA-2 siRNA (h) - sc-62902 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTP IA-2 shRNA Plasmid (h) - sc-62902-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTP IA-2 shRNA (h) Lentiviral Particles - sc-62902-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IA-2/PTPRN RNAi - H00005798-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU029231 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0816 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0814 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0815 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17716 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17716 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PTPRN siRNA (Human) - CRH3920 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PTPRN (NM_002846.3) - SHH386780 from Creative biogene

Category siRNA
Species Reactivities Human

Human PTPRN siRNA - orb264422 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PTPRN shRNA Plasmid (Human) - CHH3920 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PTPRN miRNA 3'UTR clone - MiUTR3H-04406 from Creative biogene

Species Reactivities Human
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