PTPRN

Gene Symbol PTPRN
Entrez Gene 5798
Alt Symbol IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, N
Other Description ICA 512|PTP IA-2|islet cell antigen 2|islet cell antigen 512|islet cell autoantigen 3|protein tyrosine phosphatase-like N|receptor-type tyrosine-protein phosphatase-like N
Swissprots Q53QD6 Q08319 B4DK12 Q6NSL1 F5GZS3 Q16849
Accessions AAY24038 EAW70724 EAW70725 EAW70726 Q16849 AB209368 BAD92605 AK054765 AK122679 BAG53662 AK291469 BAF84158 AK294490 BAG57712 AK296335 BAG59024 AK314574 BC007713 AAH07713 BC070053 AAH70053 BT006975 AAP35621 DC344431 DC352946 L18983 AAA90974 X62899 CAA44688 XM_011511566 XP_011509868 NM_001199763 NP_001186692 NM_001199764 NP_001186693 NM_002846 NP_002837
Function Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. {ECO:0000269|PubMed:8144912, ECO:0000269|PubMed:8641276}.
Subcellular Location Membrane; Single-pass type I membrane protein. Note=Neuroendocrine secretory granules.
Tissue Specificity Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary. {ECO:0000269|PubMed:8024693}.
Top Pathways Type I diabetes mellitus

PTPRN 293T Cell Transient Overexpression Lysate(Denatured) - H00005798-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

IA-2/PTPRN Overexpression Lysate (Denatured) - H00005798-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
PTPRN transfected lysate

IA-2/PTPRN Overexpression Lysate (Denatured) - H00005798-T02 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

PTP IA-2 (h): 293T Lysate - sc-158898 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

IA-2/PTPRN Overexpression Lysate (Denatured) - H00005798-T03 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human PTPRN Knockdown Stable Cell Line - CSC-DC012724 from Creative biogene

Category Cell Line
Species Human
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