ZNF423

Gene Symbol ZNF423
Entrez Gene 23090
Alt Symbol Ebfaz, JBTS19, NPHP14, OAZ, Roaz, ZFP423, Zfp104
Species Human
Gene Type protein-coding
Description zinc finger protein 423
Other Description OLF-1/EBF associated zinc finger|Smad- and Olf-interacting zinc finger protein|early B-cell factor associated zinc finger protein|hOAZ|olf1/EBF-associated zinc finger protein
Swissprots O94860 Q76N04 Q9NZ13 Q2M1K9
Accessions EAW82735 Q2M1K9 AB018303 BAA34480 AF221712 AAF28354 AK027479 BAG51329 AK304829 BAH14263 AK309835 AK314742 AW022965 BC112315 AAI12316 BC112317 AAI12318 BU733621 CD626621 CN396210 HQ258687 ADR83438 XM_005255856 XP_005255913 XM_005255857 XP_005255914 XM_006721171 XP_006721234 XM_011522962 XP_011521264 NM_001271620 NP_001258549 NM_015069 NP_055884
Function Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation. {ECO:0000269|PubMed:10660046}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10660046}.
Tissue Specificity Expressed in brain, lung, skeletal muscle, heart, pancreas and kidney but not liver or placenta. Also expressed in aorta, ovary, pituitary, small intestine, fetal brain, fetal kidney and, within the adult brain, in the substantia nigra, medulla, amygdala, thalamus and cerebellum. {ECO:0000269|PubMed:10660046}.

OAZ (E-6) - sc-393904 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
OAZ (E-6): sc-393904. Western blot analysis of OAZ expression in non-transfected: sc-117752 (A) and human OAZ transfected: sc-373007 (B) 293T whole cell lysates.

OAZ (E-20) - sc-10488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

OAZ (D-15) - sc-10485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
OAZ (D-15): sc-10485. Western blot analysis of human recombinant OAZ fusion protein.

OAZ (D-16) - sc-10486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
OAZ (D-16): sc-10486. Western blot analysis of human recombinant OAZ fusion protein.

OAZ (H-105) - sc-48785 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
OAZ (H-105): sc-48785. Western blot analysis of OAZ expression in non-transfected: sc-117752 (A) and human OAZ transfected: sc-373007 (B) 293T whole cell lysates.

Anti-ZNF423 antibody - ab169096 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZNF423 antibody (ab169096) at 0.4 µg/mlLane 1 : 293T cell lysateLane 2 : HeLa cell lysateLane 3 : Jurkat cell lysateLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-ZNF423 antibody - ab94451 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ZNF423 antibody (ab94451) at 1 µg/ml (in 5% skim milk / PBS buffer) + HT1080 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-ZNF423 antibody - ab87308 from Abcam

Prices $242.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
IHC-P image of ZNF423 staining on mouse lymph node section using ab87308 (dilution 1/50). The section was subjected to heat mediated antigen retrieval using citric buffer pH 6. The section were blocked using 10% serum.See Abreview

Anti-ZNF423 antibody - N-terminal - ab189608 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZNF423 antibody - N-terminal (ab189608) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : HeLa total cell extract

Anti-ZNF423 / OAZ Antibody (aa31-45) - LS-C112645 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ZNF423 / OAZ Antibody (aa250-300) - LS-C290662 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human OAZ by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, HeLa, and Jurkat cells. Antibodies: Affinity purified rabbit anti-OAZ antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-ZNF423 / OAZ Antibody (C-Terminus) - LS-C110352 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ZNF423 antibody LS-C110352 Western blot of HT1080 cell lysate.

Anti-ZNF423 / OAZ Antibody (aa1234-1284) - LS-C290663 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Detection of Human OAZ by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, HeLa, and Jurkat cells. Antibodies: Affinity purified rabbit anti-OAZ antibody used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-ZNF423 / OAZ Antibody (aa864-897) - LS-C344626 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from human brain tissue lysate with ZNF423 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

ZNF423 Antibody - NBP1-80329 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZNF423 Antibody [NBP1-80329] - Titration: 0.2-1 ug/ml, Positive Control: HT1080 cell lysate.

ZNF423 Antibody - NBP2-30695 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ZNF423 Antibody [NBP2-30695] - Immunofluorescent staining of human cell line A-431 shows positivity in nuclei. Antibody staining is shown in green.

ZNF423/OAZ Polyclonal Antibody - bs-11973R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZNF423/OAZ Polyclonal Antibody - bs-12220R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-ZNF423/OAZ Polyclonal Antibody, Unconjugated (bs-12220R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Rabbit Anti-ZNF423/OAZ Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11973R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-ZNF423/OAZ Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11973R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-ZNF423/OAZ Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11973R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-ZNF423/OAZ Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11973R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-ZNF423/OAZ Polyclonal Antibody, Cy3 Conjugated - bs-11973R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-ZNF423/OAZ Polyclonal Antibody, Cy5 Conjugated - bs-11973R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-ZNF423/OAZ Polyclonal Antibody, Cy5.5 Conjugated - bs-11973R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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