Gene Symbol | RAD51AP1 |
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Entrez Gene | 10635 |
Alt Symbol | PIR51 |
Species | Human |
Gene Type | protein-coding |
Description | RAD51 associated protein 1 |
Other Description | RAD51-associated protein 1|RAD51-interacting protein |
Swissprots | Q7Z779 A8K7D3 O43403 Q96B01 |
Accessions | EAW88843 EAW88844 Q96B01 AF006259 AAC39554 AK096930 BAC04902 AK290428 BAF83117 AK291948 BAF84637 AK300773 BAG62437 AK309706 AK316367 BAH14738 AL832243 BC005973 BC006992 AAH06992 BC016330 AAH16330 BU689445 DC397655 HQ447239 ADQ31726 JF432673 ADZ15890 XM_011520911 XP_011519213 NM_001130862 NP_001124334 NM_006479 NP_006470 |
Function | May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. {ECO:0000269|PubMed:20871616, ECO:0000269|PubMed:9396801}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Colocalizes with RAD51 to multiple nuclear foci. {ECO:0000250}. |
Tissue Specificity | Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes. {ECO:0000269|PubMed:9396801}. |
RAD51AP1 (F-14) - sc-240802 from Santa Cruz Biotechnology
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RAD51AP1 (S-15) - sc-240798 from Santa Cruz Biotechnology
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Anti-RAD51AP1 antibody - ab101321 from Abcam
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Anti-RAD51AP1 antibody - ab88370 from Abcam
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Anti-RAD51AP1 antibody - ab96666 from Abcam
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Anti-RAD51AP1 antibody - ab15957 from Abcam
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Anti-RAD51AP1 Antibody IHC-plus⢠- LS-B4839 from LifeSpan Bioscience
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Anti-RAD51AP1 Antibody (aa302-352) - LS-C289006 from LifeSpan Bioscience
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Anti-RAD51AP1 Antibody (aa250-300) - LS-C289005 from LifeSpan Bioscience
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Anti-RAD51AP1 Antibody (aa215-264) - LS-C107498 from LifeSpan Bioscience
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Anti-RAD51AP1 Antibody (aa143-192) - LS-C116178 from LifeSpan Bioscience
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Anti-RAD51AP1 Antibody (aa340-352) IHC-plus⢠- LS-B11167 from LifeSpan Bioscience
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RAD51AP1 Antibody - NBP2-13197 from Novus Biologicals
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RAD51AP1 Antibody - H00010635-B02 from Novus Biologicals
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RAD51AP1 Antibody - NB100-1129 from Novus Biologicals
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RAD51AP1 Antibody - NBP1-26637 from Novus Biologicals
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RAD51AP1 Antibody - NBP1-26638 from Novus Biologicals
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RAD51AP1 Antibody - NBP1-31046 from Novus Biologicals
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RAD51AP1 Antibody - NBP2-20060 from Novus Biologicals
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RAD51AP1 Antibody - H00010635-B01 from Novus Biologicals
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RAD51AP1 Antibody - H00010635-B02P from Novus Biologicals
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Anti-RAD51AP1 antibody produced in rabbit - HPA051499 from Sigma-Aldrich
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Anti-RAD51AP1 antibody produced in rabbit - SAB2104702 from Sigma-Aldrich
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Anti-RAD51AP1 (C-terminal) antibody produced in goat - SAB2501792 from Sigma-Aldrich
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Anti-RAD51AP1 antibody produced in rabbit - SAB2105434 from Sigma-Aldrich
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