Gene Symbol | RAD51AP1 |
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Entrez Gene | 10635 |
Alt Symbol | PIR51 |
Species | Human |
Gene Type | protein-coding |
Description | RAD51 associated protein 1 |
Other Description | RAD51-associated protein 1|RAD51-interacting protein |
Swissprots | Q7Z779 A8K7D3 O43403 Q96B01 |
Accessions | EAW88843 EAW88844 Q96B01 AF006259 AAC39554 AK096930 BAC04902 AK290428 BAF83117 AK291948 BAF84637 AK300773 BAG62437 AK309706 AK316367 BAH14738 AL832243 BC005973 BC006992 AAH06992 BC016330 AAH16330 BU689445 DC397655 HQ447239 ADQ31726 JF432673 ADZ15890 XM_011520911 XP_011519213 NM_001130862 NP_001124334 NM_006479 NP_006470 |
Function | May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. {ECO:0000269|PubMed:20871616, ECO:0000269|PubMed:9396801}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Colocalizes with RAD51 to multiple nuclear foci. {ECO:0000250}. |
Tissue Specificity | Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes. {ECO:0000269|PubMed:9396801}. |
Human RAD51AP1 full length protein - ab132169 from Abcam
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Human RAD51AP1 peptide - ab23286 from Abcam
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RAD51AP1 Antibody Blocking Peptide - LS-E14881 from LifeSpan Bioscience
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RAD51AP1 Antibody Blocking Peptide - LS-E14882 from LifeSpan Bioscience
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RAD51AP1 Antibody Blocking Peptide - LS-E25446 from LifeSpan Bioscience
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Recombinant Human RAD51AP1 Protein - H00010635-P01 from Novus Biologicals
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RAD51AP1 blocking peptide - GTX15957-PEP from GeneTex
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RAD51AP1 Blocking Peptide - 33R-4022 from Fitzgerald
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RAD51AP1 Blocking Peptide - 33R-2308 from Fitzgerald
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RAD51AP1 Peptide - AC21-0275-P from Abcore
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RAD51AP1 - H00010635-P01-02 from Acris Antibodies
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PIR51 Peptide - 46-192P from ProSci
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RAD51AP1 fusion protein - ag1781 from Proteintech Group
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Recombinant Human RAD51-associated protein 1(RAD51AP1) - CSB-YP850261HU CSB-EP850261HU CSB-BP850261HU CSB-MP850261HU from Cusabio
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PIR51/RAD51AP1, Peptide - MBS426806 from MyBioSource
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RAD51AP1 Protein - NBP2-13197PEP from Novus Biologicals
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RAD51AP1 Peptide, Human - M34GP12912H from Creative Peptides
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RAD51AP1 Immunizing peptide - orb17304 from Biorbyt
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RAD51-associated protein 1 (RAD51AP1), Recombinant Protein - MBS1316344 from MyBioSource
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Recombinant Human RAD51AP1 Protein, GST-tagged - RAD51AP1-485H from Creative Biomart
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