Gene Symbol | RAD51AP1 |
---|---|
Entrez Gene | 10635 |
Alt Symbol | PIR51 |
Species | Human |
Gene Type | protein-coding |
Description | RAD51 associated protein 1 |
Other Description | RAD51-associated protein 1|RAD51-interacting protein |
Swissprots | Q7Z779 A8K7D3 O43403 Q96B01 |
Accessions | EAW88843 EAW88844 Q96B01 AF006259 AAC39554 AK096930 BAC04902 AK290428 BAF83117 AK291948 BAF84637 AK300773 BAG62437 AK309706 AK316367 BAH14738 AL832243 BC005973 BC006992 AAH06992 BC016330 AAH16330 BU689445 DC397655 HQ447239 ADQ31726 JF432673 ADZ15890 XM_011520911 XP_011519213 NM_001130862 NP_001124334 NM_006479 NP_006470 |
Function | May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. {ECO:0000269|PubMed:20871616, ECO:0000269|PubMed:9396801}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Colocalizes with RAD51 to multiple nuclear foci. {ECO:0000250}. |
Tissue Specificity | Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes. {ECO:0000269|PubMed:9396801}. |
RAD51AP1 CRISPR/Cas9 KO Plasmid (h) - sc-408187 from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 HDR Plasmid (h) - sc-408187-HDR from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 Double Nickase Plasmid (h) - sc-408187-NIC from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 Double Nickase Plasmid (h2) - sc-408187-NIC-2 from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 CRISPR Activation Plasmid (h) - sc-408187-ACT from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 CRISPR Activation Plasmid (h2) - sc-408187-ACT-2 from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 Lentiviral Activation Particles (h) - sc-408187-LAC from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 Lentiviral Activation Particles (h2) - sc-408187-LAC-2 from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 siRNA (h) - sc-95792 from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 shRNA Plasmid (h) - sc-95792-SH from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 shRNA (h) Lentiviral Particles - sc-95792-V from Santa Cruz Biotechnology
|
||||||||
RAD51AP1 RNAi - H00010635-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU085571 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN17898 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17898 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR07886 from Sigma-Aldrich
|
||||||||
RAD51AP1 siRNA (Human) - CRH7246 from Cohesion Biosciences
|
||||||||
RAD51AP1 - MBS8220468 from MyBioSource
|
||||||||
shRNA set against Human RAD51AP1 (NM_006479.4) - SHH389008 from Creative biogene
|
||||||||
RAD51AP1 shRNA Plasmid (Human) - CHH7246 from Cohesion Biosciences
|
||||||||
RAD51AP1 miRNA 3'UTR clone - MiUTR3H-05620 from Creative biogene
|
||||||||
RAD51AP1 miRNA 3'UTR clone - MiUTR3H-05621 from Creative biogene
|