Gene Symbol | TFPI |
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Entrez Gene | 7035 |
Alt Symbol | EPI, LACI, TFI, TFPI1 |
Species | Human |
Gene Type | protein-coding |
Description | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
Other Description | anti-convertin|extrinsic pathway inhibitor|tissue factor pathway inhibitor |
Swissprots | P10646 Q53TS4 O95103 |
Accessions | AAA59480 AAA59526 AAO89075 AAY14807 EAX10921 EAX10922 EAX10923 P10646 AB209866 BAD93103 AF021834 AAD01700 AK130306 AK313562 BAG36336 AU136083 BC014332 BC015514 AAH15514 CA418214 HQ447091 ADQ31578 J03225 AAA52022 XM_005246818 XP_005246875 XM_005246819 XP_005246876 XM_005246820 XP_005246877 XM_006712720 XP_006712783 XM_011511707 XP_011510009 XM_011511708 XP_011510010 XM_011511709 XP_011510011 NM_001032281 NP_001027452 NM_006287 NP_006278 |
Function | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. |
Subcellular Location | Isoform Alpha: Secreted. |
Tissue Specificity | Mostly in endothelial cells. |
Top Pathways | Complement and coagulation cascades |
Active human TFPI protein fragment - ab167711 from Abcam
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Human TFPI full length protein - ab131806 from Abcam
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Human TFPI full length protein - ab171716 from Abcam
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Human TFPI peptide - ab66543 from Abcam
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Human TFPI peptide - ab23168 from Abcam
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Human TFPI protein fragment - ab152742 from Abcam
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TFPI / LACI Antibody Blocking Peptide - LS-E25208 from LifeSpan Bioscience
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TFPI / LACI Antibody Blocking Peptide - LS-E31466 from LifeSpan Bioscience
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TFPI / LACI Antibody Blocking Peptide - LS-E23019 from LifeSpan Bioscience
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TFPI / LACI Antibody Blocking Peptide - LS-E23018 from LifeSpan Bioscience
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Recombinant Human TFPI Protein - H00007035-Q01 from Novus Biologicals
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TFPI Recombinant Protein - H00007035-P01 from Novus Biologicals
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Recombinant Human TFPI Protein - NBP2-22870 from Novus Biologicals
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TFPI blocking peptide - GTX89985-PEP from GeneTex
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Recombinant Human TFPI, CF - 2974-PI-010 from R&D Systems
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Recombinant Rabbit Tissue factor pathway inhibitor (OPCA00238) - OPCA00238 from Aviva Systems Biology
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Recombinant human Tissue factor pathway inhibitor (OPCA00691) - OPCA00691 from Aviva Systems Biology
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Human TFPI His tag protein - orb83237 from Biorbyt
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Human LACI protein - orb245322 from Biorbyt
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TFPI Blocking Peptide - 33R-10735 from Fitzgerald
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TFPI protein (His tag) - 80R-3039 from Fitzgerald
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TFPI2 domain 1 protein (His tag) - 80R-1913 from Fitzgerald
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Human TFPI Protein - abx069318 from Abbexa
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Human TFPI Protein - abx069321 from Abbexa
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Human TFPI Protein - abx069322 from Abbexa
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