TFPI

Gene Symbol	TFPI
Entrez Gene	7035
Alt Symbol	EPI, LACI, TFI, TFPI1
Species	Human
Gene Type	protein-coding
Description	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Other Description	anti-convertin|extrinsic pathway inhibitor|tissue factor pathway inhibitor
Swissprots	P10646 Q53TS4 O95103
Accessions	AAA59480 AAA59526 AAO89075 AAY14807 EAX10921 EAX10922 EAX10923 P10646 AB209866 BAD93103 AF021834 AAD01700 AK130306 AK313562 BAG36336 AU136083 BC014332 BC015514 AAH15514 CA418214 HQ447091 ADQ31578 J03225 AAA52022 XM_005246818 XP_005246875 XM_005246819 XP_005246876 XM_005246820 XP_005246877 XM_006712720 XP_006712783 XM_011511707 XP_011510009 XM_011511708 XP_011510010 XM_011511709 XP_011510011 NM_001032281 NP_001027452 NM_006287 NP_006278
Function	Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Subcellular Location	Isoform Alpha: Secreted.
Tissue Specificity	Mostly in endothelial cells.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TFPI CRISPR/Cas9 KO Plasmid (h) - sc-416811 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TFPI HDR Plasmid (h) - sc-416811-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TFPI Double Nickase Plasmid (h) - sc-416811-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TFPI Double Nickase Plasmid (h2) - sc-416811-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TFPI CRISPR Activation Plasmid (h) - sc-416811-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TFPI CRISPR Activation Plasmid (h2) - sc-416811-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TFPI Lentiviral Activation Particles (h) - sc-416811-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TFPI Lentiviral Activation Particles (h2) - sc-416811-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TFPI siRNA (h) - sc-41060 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TFPI shRNA Plasmid (h) - sc-41060-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TFPI shRNA (h) Lentiviral Particles - sc-41060-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TFPI RNAi - H00007035-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU093771 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21264 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21264 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

TFPI siRNA (Human) - CRH4808 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TFPI RNAi - H00007035-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

TFPI - MBS8207087 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human TFPI (NM_006287.4) - SHH426276 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TFPI(NM_001032281.2) - SHH222954 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TFPI(NM_006287.4) - SHH222974 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TFPI(NM_001032281.2) - SHH222992 from Creative biogene Category siRNA Species Reactivities Human

Human TFPI siRNA - orb265310 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TFPI shRNA Plasmid (Human) - CHH4808 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

TFPI miRNA 3'UTR clone - MiUTR1H-10345 from Creative biogene Species Reactivities Human

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