TFPI

Gene Symbol TFPI
Entrez Gene 7035
Alt Symbol EPI, LACI, TFI, TFPI1
Species Human
Gene Type protein-coding
Description tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Other Description anti-convertin|extrinsic pathway inhibitor|tissue factor pathway inhibitor
Swissprots P10646 Q53TS4 O95103
Accessions AAA59480 AAA59526 AAO89075 AAY14807 EAX10921 EAX10922 EAX10923 P10646 AB209866 BAD93103 AF021834 AAD01700 AK130306 AK313562 BAG36336 AU136083 BC014332 BC015514 AAH15514 CA418214 HQ447091 ADQ31578 J03225 AAA52022 XM_005246818 XP_005246875 XM_005246819 XP_005246876 XM_005246820 XP_005246877 XM_006712720 XP_006712783 XM_011511707 XP_011510009 XM_011511708 XP_011510010 XM_011511709 XP_011510011 NM_001032281 NP_001027452 NM_006287 NP_006278
Function Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Subcellular Location Isoform Alpha: Secreted.
Tissue Specificity Mostly in endothelial cells.
Top Pathways Complement and coagulation cascades

TFPI (G-5) - sc-365920 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TFPI (G-5): sc-365920. Western blot analysis of TFPI expression in non-transfected: sc-110760 (A) and human TFPI transfected: sc-113167 (B) 293 whole cell lysates.

TFPI (H-120) - sc-28861 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TFPI (H-120): sc-28861. Western blot analysis of TFPI expression in K-562 whole cell lysate.

TFPI (G-6) - sc-133139 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TFPI (G-6): sc-133139. Western blot analysis of TFPI expression in non-transfected: sc-110760 (A) and human TFPI transfected: sc-113167 (B) 293 whole cell lysates.

TFPI (E-20) - sc-18712 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TFPI (E-20): sc-18712. Western blot analysis of TFPI expression in Hep G2 whole cell lysate.

TFPI (M-120) - sc-28862 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TFPI (M-120): sc-28862. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing membrane and cytoplasmic staining of trophoblastic cells.

TFPI (G-1) - sc-137126 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TFPI (G-1): sc-137126. Western blot analysis of TFPI expression in non-transfected: sc-110760 (A) and human TFPI transfected: sc-113167 (B) 293 whole cell lysates.

TFPI (C-20) - sc-18713 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TFPI (C-20): sc-18713. Western blot analysis of TFPI expression in JAR whole cell lysate.

Anti-TFPI antibody - ab180619 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse kidney tissue labelling TFPI with ab180619 at 1/100. Magnification: 200x.

Anti-TFPI antibody - ab181392 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TFPI antibody (ab181392) at 1 µg/ml + Rat small intestine tissue lysate at 15 µg

Anti-TFPI antibody - ab66544 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TFPI antibody (ab66544) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : A431 (Human epithelial carcinoma cell line) Whole Cell LysateLane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLane 5 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 6 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 7 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell LysateLane 8 : U2OS (Human osteosarcoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-TFPI antibody - ab117628 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
ab117628, at 10 µg/ml, staining TFPI in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.

Anti-TFPI antibody - ab48648 from Abcam

Prices $370.00
Sizes 150 µg
Host Rabbit
Clonality Polyclonal

Anti-TFPI antibody - ab9881 from Abcam

Prices $372.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TFPI antibody - ab61373 from Abcam

Prices $370.00
Sizes 1 mg
Host Sheep
Clonality Polyclonal

Anti-TFPI antibody - ab61385 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TFPI antibody - ab125365 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TFPI antibody (ab125365) at 1 µg/ml + 721_ B cell lysate at 10 µg

Anti-TFPI antibody - ab125420 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TFPI antibody (ab125420) at 1 µg/ml + ACHN cell lysate at 10 µg

Anti-TFPI antibody (Biotin) - ab49562 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TFPI antibody [EPR7941] - ab134151 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7941
All lanes : Anti-TFPI antibody [EPR7941] (ab134151) at 1/2000 dilution (purified)Lane 1 : U87-MG cell lysateLane 2 : Human placenta tissue lysateLysates/proteins at 20 µg per lane.SecondaryHRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG at 1/1000 dilution

Anti-TFPI antibody - C-terminal - ab190928 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TFPI / LACI Antibody (aa29-304, clone 3B1) - LS-C339918 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 3B1
IHC of paraffin-embedded Human Kidney tissue using anti-TFPI mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-TFPI / LACI Antibody (aa29-304, clone 5A2) - LS-C339822 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5A2
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-TFPI mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-TFPI / LACI Antibody (aa29-304, clone 4H9) - LS-C339824 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4H9
IHC of paraffin-embedded Human liver tissue using anti-TFPI mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-TFPI / LACI Antibody (aa29-304, clone 1E1) - LS-C339685 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFPI (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFPI.

Anti-TFPI / LACI Antibody (N-Terminus) IHC-plus™ - LS-B10121 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TFPI / LACI antibody IHC staining of human placenta, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10121 concentration 10 ug/ml.
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