Gene Symbol | SF3A3 |
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Entrez Gene | 10946 |
Alt Symbol | PRP9, PRPF9, SAP61, SF3a60 |
Species | Human |
Gene Type | protein-coding |
Description | splicing factor 3a, subunit 3, 60kDa |
Other Description | SAP 61|pre-mRNA splicing factor SF3a (60kD)|spliceosome associated protein 61|spliceosome-associated protein 61|splicing factor 3A subunit 3|splicing factor 3a, subunit 3, 60kD |
Swissprots | D3DPT5 Q5VT87 Q12874 Q15460 |
Accessions | EAX07304 EAX07305 EAX07306 Q12874 AI492088 AK026887 AK128438 BAG54674 AK222554 BAD96274 AK291181 BAF83870 AK292116 BAF84805 AK301424 BAG62952 BC002395 AAH02395 BC011523 AAH11523 BM702776 BM905122 CA443595 DQ891120 ABM82046 EU176559 ABW03360 N67022 N91991 U08815 AAA19625 XM_005270390 XP_005270447 NM_006802 NP_006793 |
Function | Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. |
Subcellular Location | Nucleus speckle. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Spliceosome |
Human SF3A3 full length protein - ab132617 from Abcam
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SF3A3 / SF3a60 Antibody Blocking Peptide - LS-E14902 from LifeSpan Bioscience
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Recombinant Human SF3A3 Protein - H00010946-P01 from Novus Biologicals
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SF3A3 Blocking Peptide - 33R-9103 from Fitzgerald
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SF3A3 / SAP61 - H00010946-P01-10 from Acris Antibodies
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SF3A3 / SAP61 - H00010946-P01-25 from Acris Antibodies
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SF3A3 fusion protein - Ag2708 from Proteintech Group
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Recombinant Human SF3A3, His-tagged - SF3A3-30078TH from Creative Biomart
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Recombinant Human SF3A3, GST-tagged - SF3A3-2612H from Creative Biomart
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Recombinant Human Splicing factor 3A subunit 3(SF3A3) - CSB-YP619637HU CSB-EP619637HU CSB-BP619637HU CSB-MP619637HU from Cusabio
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SF3A3 / SAP61 - TP303895 from Acris Antibodies
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SF3A3 Recombinant Protein Antigen - NBP1-87212PEP from Novus Biologicals
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SF3A3 Recombinant Protein Antigen - NBP2-38200PEP from Novus Biologicals
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SF3A3 Peptide, Human - M34GP14097H from Creative Peptides
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Splicing factor 3A subunit 3 (SF3A3), Recombinant Protein - MBS1420159 from MyBioSource
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