RCHY1

Gene Symbol RCHY1
Entrez Gene 25898
Alt Symbol ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363
Species Human
Gene Type protein-coding
Description ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Other Description CH-rich interacting match with PLAG1|E3 ubiquitin-protein ligase Pirh2|RING finger and CHY zinc finger domain-containing protein 1|RING finger protein 199|androgen-receptor N-terminal-interacting protein|p53-induced protein with a RING-H2 domain|zinc finger protein 363|zinc finger, CHY-type
Swissprots J3KPI0 C7E543 C7E541 E7ETW5 Q2KN33 Q59GN7 D3YRV2 B3KRG3 Q86X26 Q96PM5 Q96PR5 C7E542 E7EMC8
Accessions EAX05724 EAX05725 EAX05726 EAX05727 EAX05728 Q96PM5 AB209072 BAD92309 AF247041 AAL76101 AF255666 AAK96896 AF305424 AAL09356 AK091501 BAG52375 AK308754 AK308848 AK309555 AL050144 CAB43290 AW236209 AY888047 AAX78233 BC015464 AAH15464 BC031057 BC047393 AAH47393 BF102905 BG703058 BI913695 BP314571 BQ024871 BQ959587 CB241669 CF597260 DA197338 DB044826 DN919417 GQ129342 ACT64476 GQ129343 ACT64477 GQ250944 ACT35531 GQ250945 ACT35532 GQ250946 ACT35533 GU937000 ADD21555 HQ447979 ADQ32462 JF691538 AEO00252 JF691539 AEO00253 XM_011531838 XP_011530140 XM_011531839 XP_011530141 NM_001009922 NP_001009922 NM_001278536 NP_001265465 NM_001278537 NP_001265466 NM_001278538 NP_001265467 NM_001278539 NP_001265468 NM_015436 NP_056251 NR_037913 NR_037914 NR_103723 NR_103724 NR_103725 NM_001008925
Function Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. {ECO:0000269|PubMed:16914734, ECO:0000269|PubMed:17721809, ECO:0000269|PubMed:18006823, ECO:0000269|PubMed:19043414, ECO:0000269|PubMed:19483087, ECO:0000269|PubMed:21791603, ECO:0000269|PubMed:21994467}.
Subcellular Location Nucleus. Nucleus speckle. Cytoplasm.
Top Pathways p53 signaling pathway, Ubiquitin mediated proteolysis, Measles

RCHY1-Over-expression-Lysate - LY11766a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag RCHY1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RCHY1 gene

RCHY1 293T Cell Transient Overexpression Lysate(Denatured) - H00025898-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

RCHY1 overexpression lysate - LY402435 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

RCHY1 293 Cell Lysate - 402130 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

RCHY1 Over-expression Lysate Product - GWB-E38520 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Pirh2 Overexpression Lysate (Native) - NBL1-15244 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Pirh2 Overexpression Lysate (Adult Normal) [NBL1-15244] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Pirh2.

Pirh2 Overexpression Lysate (Denatured) - H00025898-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Pirh2 Overexpression Lysate (Denatured) - H00025898-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human RCHY1 Knockdown Stable Cell Line - CSC-DC013115 from Creative biogene

Category Cell Line
Species Human

RCHY1 Knockout Cell Line-HeLa - CSC-RT1981 from Creative biogene

Category Cell Line
Species Human

RCHY1 KO Cell Lysate-HeLa - CLKO-1841 from Creative biogene

Category Cell Lysate
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