RCHY1

Gene Symbol RCHY1
Entrez Gene 25898
Alt Symbol ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363
Species Human
Gene Type protein-coding
Description ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Other Description CH-rich interacting match with PLAG1|E3 ubiquitin-protein ligase Pirh2|RING finger and CHY zinc finger domain-containing protein 1|RING finger protein 199|androgen-receptor N-terminal-interacting protein|p53-induced protein with a RING-H2 domain|zinc finger protein 363|zinc finger, CHY-type
Swissprots J3KPI0 C7E543 C7E541 E7ETW5 Q2KN33 Q59GN7 D3YRV2 B3KRG3 Q86X26 Q96PM5 Q96PR5 C7E542 E7EMC8
Accessions EAX05724 EAX05725 EAX05726 EAX05727 EAX05728 Q96PM5 AB209072 BAD92309 AF247041 AAL76101 AF255666 AAK96896 AF305424 AAL09356 AK091501 BAG52375 AK308754 AK308848 AK309555 AL050144 CAB43290 AW236209 AY888047 AAX78233 BC015464 AAH15464 BC031057 BC047393 AAH47393 BF102905 BG703058 BI913695 BP314571 BQ024871 BQ959587 CB241669 CF597260 DA197338 DB044826 DN919417 GQ129342 ACT64476 GQ129343 ACT64477 GQ250944 ACT35531 GQ250945 ACT35532 GQ250946 ACT35533 GU937000 ADD21555 HQ447979 ADQ32462 JF691538 AEO00252 JF691539 AEO00253 XM_011531838 XP_011530140 XM_011531839 XP_011530141 NM_001009922 NP_001009922 NM_001278536 NP_001265465 NM_001278537 NP_001265466 NM_001278538 NP_001265467 NM_001278539 NP_001265468 NM_015436 NP_056251 NR_037913 NR_037914 NR_103723 NR_103724 NR_103725 NM_001008925
Function Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. {ECO:0000269|PubMed:16914734, ECO:0000269|PubMed:17721809, ECO:0000269|PubMed:18006823, ECO:0000269|PubMed:19043414, ECO:0000269|PubMed:19483087, ECO:0000269|PubMed:21791603, ECO:0000269|PubMed:21994467}.
Subcellular Location Nucleus. Nucleus speckle. Cytoplasm.
Top Pathways p53 signaling pathway, Ubiquitin mediated proteolysis, Measles

Pirh2 CRISPR/Cas9 KO Plasmid (h) - sc-416850 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pirh2 HDR Plasmid (h) - sc-416850-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pirh2 Double Nickase Plasmid (h) - sc-416850-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pirh2 Double Nickase Plasmid (h2) - sc-416850-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pirh2 CRISPR Activation Plasmid (h) - sc-416850-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pirh2 CRISPR Activation Plasmid (h2) - sc-416850-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pirh2 Lentiviral Activation Particles (h) - sc-416850-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pirh2 Lentiviral Activation Particles (h2) - sc-416850-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pirh2 siRNA (h) - sc-45424 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pirh2 shRNA Plasmid (h) - sc-45424-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pirh2 shRNA (h) Lentiviral Particles - sc-45424-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pirh2 RNAi - H00025898-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

Pirh2 RNAi - H00025898-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU048291 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18098 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18098 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RCHY1 siRNA (Human) - CRH8573 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Pirh2 RNAi - H00025898-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RCHY1 - MBS8235278 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RCHY1 (NM_015436.3) - SHH391288 from Creative biogene

Category siRNA
Species Reactivities Human

Human RCHY1 siRNA - orb269075 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RCHY1 shRNA Plasmid (Human) - CHH8573 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RCHY1 miRNA 3'UTR clone - MiUTR4H-TG07412 from Creative biogene

Species Reactivities Human
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