RCHY1

Gene Symbol RCHY1
Entrez Gene 25898
Alt Symbol ARNIP, CHIMP, PIRH2, PRO1996, RNF199, ZCHY, ZNF363
Species Human
Gene Type protein-coding
Description ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Other Description CH-rich interacting match with PLAG1|E3 ubiquitin-protein ligase Pirh2|RING finger and CHY zinc finger domain-containing protein 1|RING finger protein 199|androgen-receptor N-terminal-interacting protein|p53-induced protein with a RING-H2 domain|zinc finger protein 363|zinc finger, CHY-type
Swissprots J3KPI0 C7E543 C7E541 E7ETW5 Q2KN33 Q59GN7 D3YRV2 B3KRG3 Q86X26 Q96PM5 Q96PR5 C7E542 E7EMC8
Accessions EAX05724 EAX05725 EAX05726 EAX05727 EAX05728 Q96PM5 AB209072 BAD92309 AF247041 AAL76101 AF255666 AAK96896 AF305424 AAL09356 AK091501 BAG52375 AK308754 AK308848 AK309555 AL050144 CAB43290 AW236209 AY888047 AAX78233 BC015464 AAH15464 BC031057 BC047393 AAH47393 BF102905 BG703058 BI913695 BP314571 BQ024871 BQ959587 CB241669 CF597260 DA197338 DB044826 DN919417 GQ129342 ACT64476 GQ129343 ACT64477 GQ250944 ACT35531 GQ250945 ACT35532 GQ250946 ACT35533 GU937000 ADD21555 HQ447979 ADQ32462 JF691538 AEO00252 JF691539 AEO00253 XM_011531838 XP_011530140 XM_011531839 XP_011530141 NM_001009922 NP_001009922 NM_001278536 NP_001265465 NM_001278537 NP_001265466 NM_001278538 NP_001265467 NM_001278539 NP_001265468 NM_015436 NP_056251 NR_037913 NR_037914 NR_103723 NR_103724 NR_103725 NM_001008925
Function Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. {ECO:0000269|PubMed:16914734, ECO:0000269|PubMed:17721809, ECO:0000269|PubMed:18006823, ECO:0000269|PubMed:19043414, ECO:0000269|PubMed:19483087, ECO:0000269|PubMed:21791603, ECO:0000269|PubMed:21994467}.
Subcellular Location Nucleus. Nucleus speckle. Cytoplasm.
Top Pathways p53 signaling pathway, Ubiquitin mediated proteolysis, Measles

RCHY1 Antibody - 5754 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using RCHY1 Antibody.

Pirh2 (E-10) - sc-376127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pirh2 (E-10): sc-376127. Western blot analysis of Pirh2 expression in non-transfected: sc-117752 (A) and mouse Pirh2 transfected: sc-122593 (B) 293T whole cell lysates.

pirh2 (D-12) - sc-374505 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pirh2 (D-12): sc-374505. Western blot analysis of Pirh2 expression in non-transfected: sc-117752 (A) and mouse Pirh2 transfected: sc-122593 (B) 293T whole cell lysates.

Pirh2 (FL-261) - sc-67033 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Pirh2 (FL-261): sc-67033. Western blot analysis of Pirh2 expression in non-transfected: sc-117752 (A) and mouse Pirh2 transfected: sc-122592 (B) 293T whole cell lysates.

Pirh2 (E-11) - sc-166901 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pirh2 (E-11): sc-166901. Western blot analysis of Pirh2 expression in non-transfected: sc-117752 (A) and mouse Pirh2 transfected: sc-122593 (B) 293T whole cell lysates.

Pirh2 (C-12) - sc-166293 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pirh2 (C-12): sc-166293. Western blot analysis of Pirh2 expression in non-transfected: sc-117752 (A) and mouse Pirh2 transfected: sc-122593 (B) 293T whole cell lysates.

Pirh2 (C-18) - sc-46236 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pirh2 (C-18): sc-46236. Western blot analysis of Pirh2 expression in HeLa nuclear extract.

Pirh2 (T-18) - sc-46239 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pirh2 (T-18): sc-46239. Western blot analysis of Pirh2 expression in non-transfected: sc-117752 (A) and mouse Pirh2 transfected: sc-122593 (B) 293T whole cell lysates.

Anti-Pirh2 antibody - ab80103 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Pirh2 antibody (ab80103) at 1/50 dilution + HL60 cell line lysates at 35 µg

Anti-Pirh2 antibody - ab57152 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57152 Pirh2 antibody at 1ug/ml.

Anti-Pirh2 antibody [1H10] - ab93927 from Abcam

Host Mouse
Clonality Monoclonal
Clone 1H10
All lanes : Anti-Pirh2 antibody [1H10] (ab93927) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : A549 cell lysateLane 3 : MCF-7 cell lysateLane 4 : PC-12 cell lysate

Anti-Pirh2 antibody [EPR14980] - ab189247 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14980
All lanes : Anti-Pirh2 antibody [EPR14980] (ab189247) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : LnCaP cell lysateLane 3 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-RCHY1 / PIRH2 Antibody - LS-C91919 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RCHY1 / PIRH2 Antibody (C-Terminus) - LS-C191193 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RCHY1 / PIRH2 Antibody (aa1-50) - LS-C287253 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RCHY1 / PIRH2 Antibody (aa36-85) - LS-C110735 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RCHY1 / PIRH2 antibody LS-C110735 Western blot of Jurkat lysate.

Anti-RCHY1 / PIRH2 Antibody - LS-C155503 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of paraformaldehyde-fixed HeLa, using Pirh2 antibody at 1:500 dilution.

Anti-RCHY1 / PIRH2 Antibody (clone 1H10) IHC-plus™ - LS-B4132 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 1H10
Anti-RCHY1 / PIRH2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4132 dilution 1:200.

Pirh2 Antibody - NB100-2318 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Pirh2 Antibody [NB100-2318] - Detection of Human Pirh2 on HeLa whole cell lysate using NB100-2318.

Pirh2 Antibody (1H10) - NBP1-51604 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H10
Western Blot: Pirh2 Antibody (1H10) [NBP1-51604] - Western blot analysis using Pirh2 mouse mAb against Hela (1), A549 (2), MCF-7 (3) and PC-12 (4) cell lysate.

Pirh2 Antibody - NBP1-90098 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Pirh2 Antibody [NBP1-90098] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.

Pirh2 Antibody - NBP2-19839 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Pirh2 Antibody [NBP2-19839] - Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE gel, diluted at 1:1000.

Pirh2 Antibody - H00025898-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Pirh2 Antibody [H00025898-B01] - RCHY1 MaxPab polyclonal antibody (B01), Lot # 08032 WULz. Western Blot analysis of RCHY1 expression in human liver.

Pirh2 Antibody - H00025898-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Pirh2 Antibody [H00025898-D01P] - Analysis of RCHY1 expression in human liver.

Pirh2 Antibody (5D12) - H00025898-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5D12
Search more