NDST2

Gene Symbol	NDST2
Entrez Gene	8509
Alt Symbol	HSST2, NST2
Species	Human
Gene Type	protein-coding
Description	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
Other Description	N-HSST 2|N-heparan sulfate sulfotransferase 2|NDST-2|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2|glucosaminyl N-deacetylase/N-sulfotransferase 2
Swissprots	Q59H89 Q2TB32 P52849
Accessions	AAB97086 EAW54525 EAW54526 P52849 AB208870 BAD92107 AK293527 BAG57009 AK298957 BAG61053 AK300520 BAG62232 AK301251 BAG62818 AK303648 BAG64651 AK310580 BC018681 BC035711 AAH35711 BC110588 AAI10589 BC110589 AAI10590 U36601 AAC27120 XM_005270255 XP_005270312 XM_005270256 XP_005270313 XM_006718046 XP_006718109 XM_011540310 XP_011538612 XR_945852 NM_003635 NP_003626
Function	Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. {ECO:0000269|PubMed:10758005, ECO:0000269|PubMed:12634318, ECO:0000269|PubMed:16343444}.
Subcellular Location	Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Top Pathways	Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NDST2 protein fragment - ab160065 from Abcam Category Protein Source Wheat germ Species Human

NDST2 Antibody Blocking Peptide - LS-E7966 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

N-Deacetylase/N-Sulfotransferase 2/NDST2 Partial Recombinant Protein - H00008509-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NDST2-Antibody-C-term-Blocking-peptide - BP5759b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human NDST2, CF - 7689-ST-010 from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived, Ala81-Gly883, with C-terminal addition of HPGGGSGGGSGGGSHHHHHH

NDST2 - H00008509-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NDST2 - H00008509-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NDST2 Peptide - 7869P from ProSci Category Peptide Species Human

NDST2 fusion protein - Ag4656 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

NDST2 fusion protein - Ag6954 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human NDST2, GST-tagged - NDST2-1221H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human NDST2 - NDST2-633H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase - CSB-YP015615HU CSB-EP015615HU CSB-BP015615HU CSB-MP015615HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human NDST2 Protein, CF - 7689-ST from R&D Systems Category Protein Prices $329.00 Sizes 10 µg Source Human embryonic kidney cell, HEK293-derived Ala81-Gly883, with C-terminal addition of HPGGGSGGGSGGGSHHHHHH Species Human

N-Deacetylase/N-Sulfotransferase 2/NDST2 Recombinant Protein Antigen - NBP2-13645PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NDST2 Peptide, Human - M34GP10224H from Creative Peptides Category Peptide Source Synthetic. Species Human

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (NDST2), partial, Recombinant Protein - MBS951670 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human NDST2 Protein, CF - 7689-ST from Novus Biologicals Category Protein Prices $329.00 Sizes 10 µg Species Human

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